FTL and MYOG

Data Source:
BioGRID (two hybrid)

		FTL	MYOG
Description		ferritin light chain	myogenin
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Intracellular Ferritin Complex Membrane Azurophil Granule Lumen Autolysosome Extracellular Exosome	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Protein-DNA Complex
	Molecular Function	Iron Ion Binding Protein Binding Ferrous Iron Binding Ferric Iron Binding Identical Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Chromatin DNA Binding Sequence-specific DNA Binding Protein Dimerization Activity E-box Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Iron Ion Transport Cellular Iron Ion Homeostasis Intracellular Sequestering Of Iron Ion Neutrophil Degranulation Iron Ion Homeostasis	Ossification Regulation Of Transcription By RNA Polymerase II Cell Cycle Skeletal Muscle Tissue Development Negative Regulation Of Cell Population Proliferation Response To Gravity Positive Regulation Of Myotube Differentiation Skeletal Muscle Atrophy Positive Regulation Of Muscle Atrophy Regulation Of Skeletal Muscle Satellite Cell Proliferation Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Striated Muscle Atrophy Response To Denervation Involved In Regulation Of Muscle Adaptation Skeletal Muscle Cell Differentiation Muscle Cell Fate Commitment Skeletal Muscle Tissue Regeneration Myoblast Differentiation Positive Regulation Of Myoblast Differentiation Negative Regulation Of Glycolytic Process Positive Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Fiber Development Positive Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Muscle Cell Differentiation Positive Regulation Of Cell Cycle Arrest Cellular Response To Magnetism Cellular Response To Lithium Ion Cellular Response To Retinoic Acid Cellular Response To Tumor Necrosis Factor Cellular Response To Growth Factor Stimulus Cellular Response To Estradiol Stimulus Regulation Of Myoblast Fusion Positive Regulation Of Oxidative Phosphorylation
Pathways		Scavenging by Class A Receptors Golgi Associated Vesicle Biogenesis Neutrophil degranulation Iron uptake and transport	Myogenesis Myogenesis
Drugs		Iron Dextran Protoporphyrin Ferric pyrophosphate Sodium ferric gluconate complex Ferric pyrophosphate citrate
Diseases		Neurodegeneration with brain iron accumulation (NBIA); Hallervorden-Spatz syndrome; Neuroferritinopathy; Aceruloplasminemia
GWAS			Asthma ( 31959851 30929738) Asthma (childhood onset) ( 30929738)
Interacting Genes		29 interacting genes: CLEC4G FTH1 GADD45A GLP1R GRB2 HTT IGDCC3 KNG1 KPNA3 MAP3K12 MEOX2 MPHOSPH6 MTNR1B MYOC MYOG NTAQ1 PALS2 PIK3CA PPP1CC PTN RAP2A SDCBP SLC13A1 SMAD9 SPINK7 TAF10 USHBP1 VKORC1 ZDHHC17	61 interacting genes: ABI2 BBS4 BFSP2 BHLHA15 CALM1 CALM2 CALM3 CARM1 CCDC120 CCDC28A CDH18 CFAP53 CLUAP1 CPSF4 CSRP3 CTNNA3 EIF4E2 FAM110A FAM90A1 FBXO32 FBXO7 FIGLA FTL GEM H2AP HNF1A ID1 ID2 ID3 IKBIP IL16 KLHL42 LAMTOR5 LMO3 MAPK3 MAPKBP1 MBD3 MDFI MEF2A MEF2C MLH1 NEK6 ODAD4 PACRGL POLR2C POLR2J PRMT5 SEPTIN5 SP1 SPG21 SRF TAF6L TCF3 TLE5 TRIM43 TSSK3 TTC32 TXNDC9 USHBP1 YME1L1 ZCCHC14
Entrez ID		2512	4656
HPRD ID		00616	01167
Ensembl ID		ENSG00000087086	ENSG00000122180
Uniprot IDs		A0A384MDR3 P02792	P15173
PDB IDs		2FFX 2FG4 2FG8 3KXU 4V6B 5LG8 6TR9 6TS0 6TS1 6TSA 6TSF 6TSJ 6WX6
Enriched GO Terms of Interacting Partners?
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