SLC17A8 and TMEM120B

Data Source:
BioGRID (two hybrid)

		SLC17A8	TMEM120B
Description		solute carrier family 17 member 8	transmembrane protein 120B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Multivesicular Body Integral Component Of Membrane Integral Component Of Synaptic Vesicle Membrane Synaptic Vesicle Membrane Perikaryon Axon Terminus Excitatory Synapse Apical Dendrite Basal Dendrite Glial Limiting End-foot Pericellular Basket	Cellular_component Nuclear Inner Membrane Membrane Integral Component Of Membrane
	Molecular Function	L-glutamate Transmembrane Transporter Activity Neurotransmitter Transmembrane Transporter Activity Symporter Activity Transmembrane Transporter Activity	Molecular_function Ion Channel Activity Protein Binding
	Biological Process	Neural Retina Development Ion Transport Sodium Ion Transport Anion Transport Brain Development Sensory Perception Of Sound L-glutamate Transmembrane Transport Synaptic Transmission, Glutamatergic Regulation Of Synapse Structure Or Activity Cochlea Development Neurotransmitter Loading Into Synaptic Vesicle	Biological_process Ion Transmembrane Transport Fat Cell Differentiation Protein Heterooligomerization
Pathways		Organic anion transporters Defective SLC17A8 causes autosomal dominant deafness 25 (DFNA25)
Drugs
Diseases
GWAS		Low density lipoprotein cholesterol levels ( 32154731) Squamous cell carcinoma ( 23341777)	Blood protein levels ( 29875488) HDL cholesterol levels ( 32203549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 24026423 32888494 27863252) Mean reticulocyte volume ( 32888494) Molybdenum levels ( 26025379) Neutrophil count ( 32888494) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494 27863252) White blood cell count ( 32888494)
Interacting Genes		4 interacting genes: CYP4F2 DNAJC5 TMEM120B YIPF6	56 interacting genes: ALOX5AP ANKS6 APOA5 AQP6 AQP8 BNIP3L CCNDBP1 CD74 COMT CPLX4 CREB3L1 EBP ERGIC3 FCER1G FFAR2 FKBP7 GAD2 GJB1 GORAB GPR152 GPRC5D GPX8 HSD17B11 IFNGR2 IL7R JAGN1 JPH1 KCNJ6 LMNA LRRTM2 MGST3 MRPS18B MUC1 NCAPH2 REEP2 REEP4 RETREG3 RNF19B RNF5 SCN3B SH3GL3 SLC10A1 SLC10A6 SLC17A8 SLC18A1 SLC1A3 STOM STX2 TLCD4 TMEM139 TMEM143 TMEM14B TMEM80 TMPRSS2 TMX2 ZDHHC15
Entrez ID		246213	144404
HPRD ID		10457	19119
Ensembl ID		ENSG00000179520	ENSG00000188735
Uniprot IDs		Q8NDX2	A0PK00
PDB IDs
Enriched GO Terms of Interacting Partners?
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