ZKSCAN5 and TNNT1

Data Source:
BioGRID (two hybrid)

		ZKSCAN5	TNNT1
Description		zinc finger with KRAB and SCAN domains 5	troponin T1, slow skeletal type
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytosol Troponin Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding	Protein Binding Tropomyosin Binding Troponin T Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II	Skeletal Muscle Contraction Muscle Contraction Transition Between Fast And Slow Fiber Muscle Filament Sliding Slow-twitch Skeletal Muscle Fiber Contraction Sarcomere Organization Negative Regulation Of Muscle Contraction
Pathways		Generic Transcription Pathway	Striated Muscle Contraction
Drugs
Diseases			Nemaline myopathy
GWAS		Dehydroepiandrosterone sulphate levels ( 21533175) Facial emotion recognition (sad faces) ( 28608620) Femoral neck bone mineral density ( 29499414) Hand grip strength ( 29691431) Hormone measurements ( 23696881) Lumbar spine bone mineral density ( 29499414) Serum metabolite levels ( 23093944) Sex hormone levels ( 26014426) Tacrolimus trough concentration in kidney transplant patients ( 29160300) Total body bone mineral density ( 29304378) Urinary metabolite levels in chronic kidney disease ( 31959995) White blood cell count ( 32888494)	Height ( 31562340)
Interacting Genes		4 interacting genes: SUV39H1 TNNT1 ZBTB9 ZSCAN1	69 interacting genes: ARMC8 BLOC1S2 BMPR1B CCDC136 CCDC85B CHD3 CLIP4 DDX5 EEF1G FAF1 FXR2 FYN HAP1 HMGXB4 HSP90AB1 IMMT KAT5 KRT27 KRT40 LARP1 LDOC1 MARS1 MORF4L1 MYOM2 NACAD NAGK NFE2L2 NINL NSG2 OSBP2 OSM PI4KA PLEKHF1 PNMA1 PPFIA1 PRKG1 PSMC5 SBK3 SDCBP2 SEC31A SERPINA4 SH3GL3 SMAD1 SMAD2 SMURF1 SNW1 TBPL1 TFIP11 TGFBR1 TMEM98 TNNC1 TNNI1 TNNI2 TNNI3 TNNT2 TPM1 TPM3 TRA2A TRIM63 TSPYL2 TULP3 UBE2D1 VIM WDCP ZC3H15 ZKSCAN5 ZMYND19 ZNF250 ZNF768
Entrez ID		23660	7138
HPRD ID		10318	01841
Ensembl ID		ENSG00000196652	ENSG00000105048
Uniprot IDs		B3KNK8 Q8N718 Q9Y2L8	P13805
PDB IDs		2EM5 2EMM 2EMZ 2EN3 2EOM 2EON 2EOO 2YSO 2YTG
Enriched GO Terms of Interacting Partners?
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