PLA2G15 and COG4

Data Source:
BioGRID (affinity chromatography technology)

		PLA2G15	COG4
Description		phospholipase A2 group XV	component of oligomeric golgi complex 4
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleoplasm Lysosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Golgi Membrane Cytosol Golgi Transport Complex Trans-Golgi Network Membrane
	Molecular Function	Lysophospholipase Activity Triglyceride Lipase Activity Phospholipid Binding Zinc Ion Binding O-acyltransferase Activity Phospholipase A1 Activity Acylglycerol O-acyltransferase Activity Calcium-independent Phospholipase A2 Activity Phosphatidylserine 1-acylhydrolase Activity 1-acyl-2-lysophosphatidylserine Acylhydrolase Activity Phosphatidyl Phospholipase B Activity Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine) Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)	Protein Binding
	Biological Process	Lipid Metabolic Process Phospholipid Metabolic Process Glycerophospholipid Metabolic Process Diacylglycerol Biosynthetic Process Phosphatidylserine Metabolic Process Ceramide Metabolic Process Fatty Acid Catabolic Process Phosphatidylcholine Catabolic Process Phosphatidylethanolamine Catabolic Process Phosphatidylcholine Metabolic Process Phosphatidylglycerol Metabolic Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Protein Transport Golgi Vesicle Prefusion Complex Stabilization
Pathways		Hydrolysis of LPC	COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Eosinophil counts ( 27863252) Eosinophil percentage of white cells ( 27863252) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Brain morphology (MOSTest) ( 32665545) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Malaria ( 31844061) Menarche (age at onset) ( 25231870) Weight ( 28552196)
Interacting Genes		2 interacting genes: IMMT RNF7	15 interacting genes: ANKRD11 APC BEX2 COG1 COG2 COG5 COG7 CTNNA3 FAM110A FARSA MTNR1B PSMA1 SEPTIN2 SORBS3 TXNDC9
Entrez ID		23659	25839
HPRD ID		07128	08444
Ensembl ID		ENSG00000103066	ENSG00000103051
Uniprot IDs		Q8NCC3	A0A0A0MS45 J3KNI1 Q8N8L9 Q9H9E3
PDB IDs		4X90 4X91 4X92 4X93 4X94 4X95 4X97 6MTW	3HR0
Enriched GO Terms of Interacting Partners?
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