SH3BP1 and TRIP10

Data Source:
BioGRID (two hybrid)

		SH3BP1	TRIP10
Description		SH3 domain binding protein 1	thyroid hormone receptor interactor 10
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GO Annotations	Cellular Component	Exocyst Phagocytic Cup Intracellular Anatomical Structure Nucleus Cytosol Adherens Junction Bicellular Tight Junction Lamellipodium Cell Leading Edge	Phagocytic Cup Nucleoplasm Cytoplasm Lysosome Golgi Apparatus Cytosol Cytoskeleton Cell Cortex Cell Projection Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	GTPase Activator Activity Protein Binding SH3 Domain Binding Semaphorin Receptor Binding	Protein Binding Lipid Binding Identical Protein Binding
	Biological Process	Phagocytosis, Engulfment Actin Filament Organization Cell Migration Regulation Of Actin Filament Depolymerization Regulation Of Actin Cytoskeleton Organization Cell Junction Assembly Regulation Of Rac Protein Signal Transduction Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of GTPase Activity Establishment Of Epithelial Cell Apical/basal Polarity Filopodium Assembly Negative Regulation Of Small GTPase Mediated Signal Transduction Semaphorin-plexin Signaling Pathway Ruffle Assembly	Endocytosis Cell Communication Signal Transduction Actin Cytoskeleton Organization Regulation Of Small GTPase Mediated Signal Transduction Membrane Organization
Pathways			Rho GTPase cycle Clathrin-mediated endocytosis
Drugs
Diseases
GWAS
Interacting Genes		14 interacting genes: ABI2 ABI3 ABL1 CCDC146 CRK FGA HCK POT1 RAC1 RHOA SRC SYNJ1 TERF1 TRIP10	41 interacting genes: ABI1 ABL2 AKAP9 ARHGAP12 ARHGAP17 CDC42 CREBBP CTNNB1 DNM2 DTX3 HOXC11 HTT JRK LYN MEOX1 MEOX2 NKX2-5 PAX6 PDE6G POT1 PRKACA RHOJ RHOQ RIN1 RXRA SF3A2 SH3BP1 SMARCE1 SMURF1 SRC STAT3 TERF1 THAP1 THRB TINF2 UTF1 WAS WASF1 WASL WBP11 ZBTB7B
Entrez ID		23616	9322
HPRD ID		10227	05142
Ensembl ID		ENSG00000100092	ENSG00000125733
Uniprot IDs		A0A2X0SFX7 Q9Y3L3	Q15642 W4VSQ9
PDB IDs		4J9D 4J9F	2CT4 2EFK 2KE4
Enriched GO Terms of Interacting Partners?
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