ZNF346 and MIRLET7F1

Data Source:
BioGRID (unspecified method)

		ZNF346	MIRLET7F1
Description		zinc finger protein 346	microRNA let-7f-1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm	Extracellular Space Extracellular Exosome
	Molecular Function	RNA Binding Double-stranded RNA Binding Protein Binding Zinc Ion Binding Enzyme Binding MiRNA Binding	MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process		Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of TOR Signaling Negative Regulation Of Interleukin-17 Production Gene Silencing By MiRNA Negative Regulation Of Apoptotic Process Negative Regulation Of Protein Kinase B Signaling Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Cellular Response To Amyloid-beta
Pathways
Drugs
Diseases
GWAS		Height ( 28552196 31562340) Type 2 diabetes ( 30718926) Uterine fibroids ( 30194396 31649266) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		66 interacting genes: ADARB1 ANKHD1 EIF2AK2 ILF3 LNX1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR141 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18B MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR214 MIR221 MIR222 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A2 MIR98 MIRLET7A1 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7I NKRF RNF8 STRBP TARBP2 XPO5	93 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B ATXN2L C1QBP CELF1 DARS1 DDX1 DDX21 DDX3X DDX3Y DHX37 EIF2AK2 EPRS1 ERAL1 FAM98A FAM98B FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PGAM5 PLOD1 PRMT1 PTBP1 PUM1 PUM2 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RBM47 RTCA RTCB SART3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYNCRIP TAF15 TRA2A TRA2B TUT4 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346
Entrez ID		23567	406888
HPRD ID		05606
Ensembl ID		ENSG00000113761	ENSG00000199072
Uniprot IDs		B7Z4J8 B7Z4N4 Q9UL40
PDB IDs		2MKD 2MKN
Enriched GO Terms of Interacting Partners?
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