SPIDR and FIGNL1

Data Source:
BioGRID (pull down)

		SPIDR	FIGNL1
Description		scaffold protein involved in DNA repair	fidgetin like 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Nucleoplasm	Nuclear Chromosome Nucleus Cytoplasm Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding	Magnesium Ion Binding Protein Binding ATP Binding Microtubule-severing ATPase Activity Hydrolase Activity ATPase Activity
	Biological Process	Double-strand Break Repair Via Homologous Recombination Cellular Response To DNA Damage Stimulus Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Protein-containing Complex Assembly Regulation Of Establishment Of Protein Localization To Chromosome Cellular Response To Ionizing Radiation Cellular Response To Hydroxyurea Cellular Response To Camptothecin Positive Regulation Of Double-strand Break Repair	Osteoblast Differentiation Male Meiotic Nuclear Division Regulation Of Double-strand Break Repair Via Homologous Recombination Cytoplasmic Microtubule Organization Osteoblast Proliferation Negative Regulation Of Apoptotic Process ATP Metabolic Process Microtubule Severing Regulation Of Cell Cycle Cellular Response To Ionizing Radiation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Resolution of D-loop Structures through Holliday Junction Intermediates
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Monocyte percentage of white cells ( 32888494)	Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Crohn's disease ( 21102463)
Interacting Genes		2 interacting genes: BLM FIGNL1	8 interacting genes: C1orf112 DMC1 GCC1 IDH1 ITGB1BP1 KDM1A RAD51 SPIDR
Entrez ID		23514	63979
HPRD ID		19305	10958
Ensembl ID		ENSG00000164808	ENSG00000132436
Uniprot IDs		Q14159	B3KNH6 Q6PIW4
PDB IDs			3D8B
Enriched GO Terms of Interacting Partners?
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