TNFRSF13B and B9D1

Data Source:
BioGRID (proximity labelling technology)

		TNFRSF13B	B9D1
Description		TNF receptor superfamily member 13B	B9 domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Centrosome Cytosol Ciliary Transition Zone MKS Complex Ciliary Basal Body
	Molecular Function	Protein Binding Signaling Receptor Activity	Protein Binding Hedgehog Receptor Activity
	Biological Process	B Cell Homeostasis Hematopoietic Progenitor Cell Differentiation Adaptive Immune Response Cell Surface Receptor Signaling Pathway Negative Regulation Of B Cell Proliferation Tumor Necrosis Factor-mediated Signaling Pathway	Smoothened Signaling Pathway Cilium Assembly Ciliary Basal Body-plasma Membrane Docking
Pathways		TNFs bind their physiological receptors	Anchoring of the basal body to the plasma membrane
Drugs
Diseases		Common variable immunodeficiency (CVID), including the following four diseases: Inducible T Cell costimulator (ICOS) defect; TACI defect; CD19 defect; BAFFR defect
GWAS		Albumin-globulin ratio ( 29403010) Apolipoprotein A1 levels ( 32203549) Diabetic retinopathy ( 21441570) Granulocyte percentage of myeloid white cells ( 27863252) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Hematological and biochemical traits ( 20139978) Hematology traits ( 23303382) IgG levels ( 22673310) Immunoglobulin light chain (AL) amyloidosis ( 28025584) Immunoglobulin measurement (zinc sulfate turbidity test) ( 29403010) Lymphocyte counts ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monoclonal gammopathy of undetermined significance ( 30737484) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Multiple myeloma ( 32569378 26007630 23955597) Multiple myeloma and monoclonal gammopathy ( 26007630) Neutrophil percentage of white cells ( 32888494) Non-albumin protein levels ( 22558069 29403010) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) Serum albumin level ( 29403010) Serum total protein level ( 23022100 29403010) Sodium levels ( 29403010) Tonsillectomy ( 27182965 28928442) White blood cell count ( 32888494)
Interacting Genes		7 interacting genes: CAMLG SGTA TNFSF13 TNFSF13B TRAF2 TRAF5 TRAF6	2 interacting genes: EXOSC10 LIG4
Entrez ID		23495	27077
HPRD ID		05365	16866
Ensembl ID		ENSG00000240505	ENSG00000108641
Uniprot IDs		O14836 Q4ACX1	A0A0B4J223 A0A2R8Y646 A0A6Q8PFJ7 A8MYG7 B4DEW0 B4DN64 Q9UPM9
PDB IDs		1XU1 1XUT
Enriched GO Terms of Interacting Partners?
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