TRAM1 and TCF20

Data Source:
BioGRID (biochemical)

		TRAM1	TCF20
Description		translocation associated membrane protein 1	transcription factor 20
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane	Nucleus Nucleoplasm Nuclear Body
	Molecular Function	Protein Binding Signaling Receptor Activity	DNA Binding RNA Binding Protein Binding Metal Ion Binding
	Biological Process	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Viral Process Protein Insertion Into ER Membrane	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS		Cardiac Troponin-T levels ( 23247143) Erythrocyte cadmium concentration in never smokers ( 27005419) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Antisaccade task score ( 31596458) Arterial stiffness ( 31070453) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 29273807) Chronotype ( 30696823) Cognitive function ( 25644384) Intelligence ( 28530673) Isthmus-cingulate cortex volume ( 31530798) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656 30285260)
Interacting Genes		12 interacting genes: APP CREB3 DRD2 ESR1 ESR2 GUCA2A SEC61B TICAM1 TIRAP TRAF6 UBC VKORC1	8 interacting genes: AR ESR1 H2AC20 H2BC21 JUN MAPK14 RNF4 SMAD1
Entrez ID		23471	6942
HPRD ID		05545	04378
Ensembl ID		ENSG00000067167	ENSG00000100207
Uniprot IDs		G3XAN4 Q15629 Q6FHL3	Q9UGU0 W5ZR30
PDB IDs
Enriched GO Terms of Interacting Partners?
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