ABCB9 and CIT

Data Source:
BioGRID (affinity chromatography technology)

		ABCB9	CIT
Description		ATP binding cassette subfamily B member 9	citron rho-interacting serine/threonine kinase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Early Endosome Endoplasmic Reticulum Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane MHC Class I Peptide Loading Complex Intracellular Membrane-bounded Organelle	Cytoplasm Cytosol Cytoskeleton Membrane
	Molecular Function	Protein Binding ATP Binding ABC-type Peptide Antigen Transporter Activity ABC-type Peptide Transporter Activity ATPase Activity Transmembrane Transporter Activity MHC Class I Protein Binding ATPase-coupled Transmembrane Transporter Activity Protein Homodimerization Activity TAP1 Binding	Transcription Coactivator Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding SH3 Domain Binding Protein Kinase Binding PDZ Domain Binding Protein Serine/threonine Kinase Inhibitor Activity Metal Ion Binding Scaffold Protein Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Protein Transport Peptide Transport Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Transmembrane Transport	Mitotic Cell Cycle Mitotic Cytokinesis Peptidyl-threonine Phosphorylation Actomyosin Structure Organization Positive Regulation Of Cytokinesis Negative Regulation Of Hippo Signaling Intracellular Signal Transduction Generation Of Neurons Neuron Apoptotic Process Negative Regulation Of Protein Serine/threonine Kinase Activity
Pathways		ABC-family proteins mediated transport	RHO GTPases activate CIT RHO GTPases activate CIT
Drugs			Fostamatinib
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Platelet count ( 21507922) Schizophrenia ( 28991256 25056061 29483656 23974872) Tourette syndrome ( 30818990) Triiodothyronine levels and thyroxine levels ( 30843173) Type 2 diabetes ( 28869590) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Number of sexual partners ( 30643258) Urgency urinary incontinence ( 25524241)
Interacting Genes			10 interacting genes: DISC1 DLG4 GRIN1 GRIN2D MTNR1A RAC1 RHOA RHOB RHOC RND3
Entrez ID		23457	11113
HPRD ID		09262	09289
Ensembl ID		ENSG00000150967	ENSG00000122966
Uniprot IDs		A0A024RBU1 Q9NP78	O14578
PDB IDs
Enriched GO Terms of Interacting Partners?
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