AP4E1 and SLC27A2

Data Source:
BioGRID (biochemical)

		AP4E1	SLC27A2
Description		adaptor related protein complex 4 subunit epsilon 1	solute carrier family 27 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	AP-4 Adaptor Complex Endosome Lumen Trans-Golgi Network Membrane	Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Integral Component Of Endoplasmic Reticulum Membrane Specific Granule Membrane Extracellular Exosome
	Molecular Function	Protein Binding Cargo Adaptor Activity	Long-chain Fatty Acid-CoA Ligase Activity Long-chain Fatty Acid Transporter Activity ATP Binding Fatty Acid Transmembrane Transporter Activity Enzyme Binding Very Long-chain Fatty Acid-CoA Ligase Activity Arachidonate-CoA Ligase Activity Cholate-CoA Ligase Activity Phytanate-CoA Ligase Activity Pristanate-CoA Ligase Activity
	Biological Process	Protein Targeting Receptor-mediated Endocytosis Protein Localization	Fatty Acid Alpha-oxidation Long-chain Fatty Acid Metabolic Process Protein Targeting To Peroxisome Fatty Acid Beta-oxidation Bile Acid Biosynthetic Process Very Long-chain Fatty Acid Catabolic Process Neutrophil Degranulation Long-chain Fatty Acid Import Into Cell Methyl-branched Fatty Acid Metabolic Process
Pathways		Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Synthesis of bile acids and bile salts via 24-hydroxycholesterol Alpha-oxidation of phytanate Neutrophil degranulation Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases		Cerebral palsy
GWAS		Chloride levels ( 29403010) Creatinine levels ( 29403010) Glomerular filtration rate ( 29403010) Height ( 31562340) Potassium levels ( 29403010) Response to fenofibrate (HDL cholesterol levels) ( 27002377)	Blood metabolite ratios ( 24816252) Platelet count ( 32888494) Verbal declarative memory ( 25648963)
Interacting Genes		3 interacting genes: AP4B1 ARF1 MTNR1B	4 interacting genes: ABCD1 PEX5 UBC YWHAQ
Entrez ID		23431	11001
HPRD ID		06258	11935
Ensembl ID		ENSG00000081014	ENSG00000140284
Uniprot IDs		B4DM48 Q9UPM8	O14975
PDB IDs
Enriched GO Terms of Interacting Partners?
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