RYBP and ZFP42

Data Source:
BioGRID (two hybrid)

		RYBP	ZFP42
Description		RING1 and YY1 binding protein	ZFP42 zinc finger protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm PcG Protein Complex	Transcription Regulator Complex Cytoplasm PcG Protein Complex
	Molecular Function	DNA Binding Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Apoptotic Process Multicellular Organism Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Histone H2A Monoubiquitination Positive Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition	Regulation Of Transcription By RNA Polymerase II Male Gonad Development Female Gonad Development Meiotic Cell Cycle
Pathways		RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 32296059) Body size at age 10 ( 32376654) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Height ( 28552196 20881960 25282103 25429064 23563607 31562340) Medication use (beta blocking agents) ( 31015401) Metabolite levels ( 23823483) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Resting-state electroencephalogram vigilance ( 29703947) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 25673412 28448500)	Cortisol levels (saliva) ( 28843169) Testicular germ cell tumor ( 28604728 28604732) Visceral fat ( 30942860)
Interacting Genes		33 interacting genes: ABL1 BANP CASP10 CASP8 CBX2 CRK E2F2 E2F3 E2F4 E2F6 EAF1 FADD FANK1 FHL3 GABPB1 GABPB2 HSPB1 MAPK8IP2 MDM2 NMI NOS1AP PSMB1 RBBP4 RING1 RNF2 RNF8 SOCS2 UBC UBE3A XAGE1A XAGE1B YY1 ZFP42	8 interacting genes: EED LHX2 MEOX2 PIAS2 RNF4 RYBP SUMO1 YAF2
Entrez ID		23429	132625
HPRD ID		09607	15726
Ensembl ID		ENSG00000163602	ENSG00000179059
Uniprot IDs		Q8N488	Q96MM3
PDB IDs		3IXS
Enriched GO Terms of Interacting Partners?
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