SMG5 and CKB

Data Source:
BioGRID (genetic interference)

		SMG5	CKB
Description		SMG5 nonsense mediated mRNA decay factor	creatine kinase B
Image
GO Annotations	Cellular Component	Nucleus Telomerase Holoenzyme Complex Cytoplasm Cytosol	Extracellular Space Nucleus Cytosol Dendrite Neuronal Cell Body Extracellular Exosome
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Telomeric DNA Binding Histone Deacetylase Binding Protein Phosphatase 2A Binding Telomerase RNA Binding	Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity Ubiquitin Protein Ligase Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Export From Nucleus Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Dephosphorylation	Creatine Metabolic Process Phosphorylation Cerebellum Development Substantia Nigra Development Cellular Chloride Ion Homeostasis Phosphocreatine Biosynthetic Process
Pathways		Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Creatine metabolism
Drugs			Creatine Phosphocreatine
Diseases
GWAS		Glycated hemoglobin levels ( 29170429) Hemoglobin A1c levels ( 29403010) Mean corpuscular hemoglobin concentration ( 29403010 20139978)	Adult body size ( 32376654) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778) Extremely high intelligence ( 29520040) Height ( 28552196 31562340) Schizophrenia ( 25056061)
Interacting Genes		7 interacting genes: APP SMG1 SMG6 SMG7 STUB1 TERT UPF1	15 interacting genes: ACD ARIH2 ASB9 CKM ERBB2 GOLGA2 ILK MLH1 POT1 PPP1CA SERP2 TAB1 TERF1 TINF2 TRIM63
Entrez ID		23381	1152
HPRD ID		16869	00423
Ensembl ID		ENSG00000198952	ENSG00000166165
Uniprot IDs		Q9UPR3	G3V4N7 P12277 V9HWH2
PDB IDs		2HWY	3B6R 3DRB 3DRE 6V9H
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?