U2SURP and MIR25

Data Source:
BioGRID (unspecified method)

		U2SURP	MIR25
Description		U2 snRNP associated SURP domain containing	microRNA 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Extracellular Space
	Molecular Function	RNA Binding Protein Binding	MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	MRNA Splicing, Via Spliceosome	Gene Silencing By MiRNA Negative Regulation Of Cardiac Muscle Tissue Growth Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 32888494) Urate levels ( 31578528)
Interacting Genes		60 interacting genes: CTNNBL1 DDX42 MIR1-1 MIR106A MIR106B MIR107 MIR10B MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR143 MIR145 MIR155 MIR15B MIR18A MIR18B MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200B MIR200C MIR205 MIR206 MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR92A1 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PRPF40A TBC1D4 TERT TRA2A	100 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CDC5L CELF1 CPSF6 CPSF7 DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EIF2AK2 ELAC1 EPRS1 ESRP1 FAM98A FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PATL1 PDCD11 PGAM5 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA PURB QARS1 RARS1 RBFOX2 RBM14 RBM17 RBM4 RBM45 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TRIM25 TRIM56 TRIM71 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3
Entrez ID		23350	407014
HPRD ID		19056
Ensembl ID		ENSG00000163714	ENSG00000207547
Uniprot IDs		O15042
PDB IDs
Enriched GO Terms of Interacting Partners?
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