VPS39 and OIP5

Data Source:
BioGRID (affinity chromatography technology)

		VPS39	OIP5
Description		VPS39 subunit of HOPS complex	Opa interacting protein 5
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Membrane AP-3 Adaptor Complex HOPS Complex Late Endosome Membrane	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromocenter Cajal Body Nuclear Speck Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Autophagy Endosome To Lysosome Transport Endosomal Vesicle Fusion Late Endosome To Lysosome Transport Retrograde Transport, Endosome To Plasma Membrane	Cell Cycle Chromosome Segregation Cell Communication CENP-A Containing Nucleosome Assembly Cell Division
Pathways			Deposition of new CENPA-containing nucleosomes at the centromere
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29785011) Ulcerative colitis ( 28067908)
Interacting Genes		7 interacting genes: HOOK1 RAB7A RILP SNW1 STAT3 TFIP11 VPS11	141 interacting genes: A1CF ABI2 ABI3 ABL2 AGXT BCAS2 BEX2 BFSP2 BLOC1S5 BRAF C1orf94 C20orf85 C21orf91 C7orf31 C7orf57 CASP10 CBY2 CCDC22 CCDC24 CCHCR1 CDR2L CEP170P1 CEP57 CERK CHCHD2 COX5B CRACR2A CTNNA3 DMRT3 DTNBP1 DTX2 DUSP21 EFHC1 EIF4ENIF1 ESS2 FAM161B FAM222B FOXJ1 FSD2 GADD45GIP1 GCC1 GEM GLIS2 GPANK1 GPS2 HAPLN2 HGS HJURP HOXB5 HOXB9 HOXC8 HSF4 IL16 KANK2 KDM1A KIF9 KLHL38 KLHL42 KNSTRN KRT14 KRT15 KRT27 KRT3 KRT35 KRT37 KRT40 KRT6B KRT75 KRT81 KRT83 KRT86 KRTAP13-2 KRTAP19-5 KRTAP19-6 LENG1 MED4 MEIS2 MGAT5B MIIP MIS18A MISP MORN3 MYEF2 MYRIP NDUFAB1 NECAB2 NUP54 NUP62 P4HA3 PATZ1 PEX19 PHETA1 PITX2 PLAGL2 POLR2J POU6F2 PPP1R32 PRR35 PSMB1 RAB26 RABGEF1 RAF1 RARG RIBC1 RUNX1T1 RUSC1 S100Z SAMD7 SAXO1 SHISA6 SKIL SMARCE1 SNRNP25 SNRPB SOHLH1 SORBS3 SPATA24 SYCE1L TEKT3 TEX12 TFAP2D TFIP11 TIMM8A TLX3 TMPO TPM3 TPRX1 TRIB3 TRIM73 TRIP6 TROAP TSSK3 USHBP1 USP2 USP54 WASHC1 YTHDF1 ZIC1 ZMAT1 ZNF417 ZNF655
Entrez ID		23339	11339
HPRD ID		10300	09352
Ensembl ID		ENSG00000166887	ENSG00000104147
Uniprot IDs		A0A024R9L9 Q96JC1	A0A024R9N0 O43482
PDB IDs		6ZE9
Enriched GO Terms of Interacting Partners?
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