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OIP5 and NUP62
Data Source:
BioGRID
(two hybrid, two hybrid)
OIP5
NUP62
Description
Opa interacting protein 5
nucleoporin 62
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Chromatin
Nucleus
Nucleoplasm
Chromocenter
Cajal Body
Nuclear Speck
Intracellular Membrane-bounded Organelle
Spindle Pole
Nuclear Envelope
Annulate Lamellae
Nuclear Pore
Nucleoplasm
Cytoplasm
Centrosome
Nuclear Membrane
Host Cell
Nuclear Pore Central Transport Channel
Mitotic Spindle
Flemming Body
Ribonucleoprotein Complex
Molecular Function
Protein Binding
Identical Protein Binding
Metal Ion Binding
Chromatin Binding
Protein Binding
Phospholipid Binding
Structural Constituent Of Nuclear Pore
Kinesin Binding
Signaling Receptor Complex Adaptor Activity
Hsp70 Protein Binding
SH2 Domain Binding
Ubiquitin Binding
Protein-containing Complex Binding
PTB Domain Binding
Hsp90 Protein Binding
Biological Process
Cell Cycle
Chromosome Segregation
Cell Communication
CENP-A Containing Nucleosome Assembly
Cell Division
Regulation Of Glycolytic Process
RNA Export From Nucleus
MRNA Export From Nucleus
TRNA Export From Nucleus
Protein Import Into Nucleus
Mitotic Metaphase Plate Congression
Centrosome Cycle
Mitotic Centrosome Separation
Cell Surface Receptor Signaling Pathway
Spermatogenesis
Cell Aging
Cell Death
Negative Regulation Of Cell Population Proliferation
Regulation Of Signal Transduction
Viral Process
Protein Sumoylation
Viral Transcription
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Protein Import Into Nucleus
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of MAP Kinase Activity
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Mitotic Nuclear Division
Positive Regulation Of Transcription, DNA-templated
Regulation Of Ras Protein Signal Transduction
Negative Regulation Of Ras Protein Signal Transduction
Positive Regulation Of Centriole Replication
Regulation Of Mitotic Spindle Organization
Regulation Of Gene Silencing By MiRNA
Intracellular Transport Of Virus
Centriole Assembly
Regulation Of Cellular Response To Heat
Positive Regulation Of Mitotic Cytokinetic Process
Positive Regulation Of Protein Localization To Centrosome
Pathways
Deposition of new CENPA-containing nucleosomes at the centromere
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
tRNA processing in the nucleus
HCMV Early Events
HCMV Late Events
Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS
Allergic disease (asthma, hay fever or eczema) (
29785011
)
Ulcerative colitis (
28067908
)
Interacting Genes
141 interacting genes:
A1CF
ABI2
ABI3
ABL2
AGXT
BCAS2
BEX2
BFSP2
BLOC1S5
BRAF
C1orf94
C20orf85
C21orf91
C7orf31
C7orf57
CASP10
CBY2
CCDC22
CCDC24
CCHCR1
CDR2L
CEP170P1
CEP57
CERK
CHCHD2
COX5B
CRACR2A
CTNNA3
DMRT3
DTNBP1
DTX2
DUSP21
EFHC1
EIF4ENIF1
ESS2
FAM161B
FAM222B
FOXJ1
FSD2
GADD45GIP1
GCC1
GEM
GLIS2
GPANK1
GPS2
HAPLN2
HGS
HJURP
HOXB5
HOXB9
HOXC8
HSF4
IL16
KANK2
KDM1A
KIF9
KLHL38
KLHL42
KNSTRN
KRT14
KRT15
KRT27
KRT3
KRT35
KRT37
KRT40
KRT6B
KRT75
KRT81
KRT83
KRT86
KRTAP13-2
KRTAP19-5
KRTAP19-6
LENG1
MED4
MEIS2
MGAT5B
MIIP
MIS18A
MISP
MORN3
MYEF2
MYRIP
NDUFAB1
NECAB2
NUP54
NUP62
P4HA3
PATZ1
PEX19
PHETA1
PITX2
PLAGL2
POLR2J
POU6F2
PPP1R32
PRR35
PSMB1
RAB26
RABGEF1
RAF1
RARG
RIBC1
RUNX1T1
RUSC1
S100Z
SAMD7
SAXO1
SHISA6
SKIL
SMARCE1
SNRNP25
SNRPB
SOHLH1
SORBS3
SPATA24
SYCE1L
TEKT3
TEX12
TFAP2D
TFIP11
TIMM8A
TLX3
TMPO
TPM3
TPRX1
TRIB3
TRIM73
TRIP6
TROAP
TSSK3
USHBP1
USP2
USP54
WASHC1
YTHDF1
ZIC1
ZMAT1
ZNF417
ZNF655
91 interacting genes:
ABI2
ADAM15
AGR3
ARFIP2
ATF7IP2
ATXN7
BFSP1
BLOC1S6
C14orf119
C1orf216
CAVIN3
CCDC121
CCDC146
CCDC150
CCDC153
CCHCR1
CENPU
CEP57L1
CLIC1
CRCT1
DDX3X
DGCR6
DPPA3
DTNB
DYNLT1
FABP3
GOPC
GORASP2
GTF2E2
HAUS1
HGS
HSF2
HSF4
HSPB11
IDH1
IFT20
IK
IKBIP
IPO5
ISCU
KANSL1
KIFC3
KLHL32
KPNA1
KPNA2
KPNB1
KRT1
KRT20
KRT3
KRT6A
KRT6B
KRT75
LMO2
LNX1
MUC1
MXD3
MYO15B
NFX1
NUP153
NUP214
NUP54
NUP58
NUP88
NUP98
NUTF2
NXF1
NXF2
OGT
OIP5
OTUD6A
PBX2
PELI2
PHF21A
PIN1
PTMA
RANBP2
SMARCE1
SNAPC5
SP1
SSC5D
SUOX
THAP1
TLE4
TRAF3
TRIML2
TXLNA
TXN
USHBP1
WASHC3
XPO1
XPO6
Entrez ID
11339
23636
HPRD ID
09352
05782
Ensembl ID
ENSG00000104147
ENSG00000213024
Uniprot IDs
A0A024R9N0
O43482
A0A024QZF1
P37198
PDB IDs
2H4D
5IJN
5IJO
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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