SATB2 and ADAM23

Data Source:
BioGRID (affinity chromatography technology)

		SATB2	ADAM23
Description		SATB homeobox 2	ADAM metallopeptidase domain 23
Image			No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Chromatin Nucleoplasm Transcription Regulator Complex Nuclear Matrix	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Glutamatergic Synapse Integral Component Of Presynaptic Membrane
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Histone Deacetylase Binding	Metalloendopeptidase Activity Integrin Binding Protein Binding Metallopeptidase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Osteoblast Development Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Embryonic Pattern Specification Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Cartilage Development Roof Of Mouth Development Cellular Response To Organic Substance	Proteolysis Cell Adhesion Central Nervous System Development Cellular Response To Leukemia Inhibitory Factor
Pathways		SUMOylation of chromatin organization proteins RUNX2 regulates osteoblast differentiation	LGI-ADAM interactions
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Brain cytoarchitecture ( 20308991) Cerebrospinal fluid immune biomarker levels ( 32066700) Chin dimples ( 27182965) Colorectal cancer or advanced adenoma ( 30510241) FEV1 ( 30804560) Heel bone mineral density ( 30598549) Height ( 31562340) Insomnia ( 23728906) Loneliness (multivariate analysis) ( 27629369) Lung function (FVC) ( 30804560) Menarche (age at onset) ( 27182965 29773799 25231870) Rheumatoid arthritis ( 30891314) Schizophrenia ( 28991256 25056061 29483656 30285260) Type 2 diabetes ( 25760438) Ulcerative colitis ( 20228799) Waist circumference ( 23966867)	Bipolar disorder and schizophrenia ( 22688191) Blood protein levels ( 30072576 29875488) Body mass index ( 28892062 25673413) Childhood body mass index ( 26604143) Fish- and plant-related diet ( 32066663) Neurological blood protein biomarker levels ( 31320639) Tonsillectomy ( 27182965 28928442) Trunk fat mass ( 28552196) Waist-hip ratio ( 28552196)
Interacting Genes		5 interacting genes: HDAC1 MTA2 PIAS1 POLR2J3 RAB3IL1	1 interacting genes: PRNP
Entrez ID		23314	8745
HPRD ID		12178	04752
Ensembl ID		ENSG00000119042	ENSG00000114948
Uniprot IDs		A0A024R3U6 B3KPQ9 Q59FT3 Q9UPW6	A0A024R3W8 E7EWD3 O75077
PDB IDs		1WI3 1WIZ 2CSF
Enriched GO Terms of Interacting Partners?
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