ANKRD28 and TGS1

Data Source:
BioGRID (two hybrid)

		ANKRD28	TGS1
Description		ankyrin repeat domain 28	trimethylguanosine synthase 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Cytosol	Extracellular Space Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Cajal Body Small Nuclear Ribonucleoprotein Complex
	Molecular Function	Protein Binding	Protein Binding RNA Methyltransferase Activity RNA Trimethylguanosine Synthase Activity
	Biological Process	COPII Vesicle Coating	Spliceosomal SnRNP Assembly 7-methylguanosine RNA Capping Regulation Of Lipid Metabolic Process Ribonucleoprotein Complex Biogenesis 7-methylguanosine Cap Hypermethylation
Pathways		Telomere Extension By Telomerase COPII-mediated vesicle transport	RORA activates gene expression BMAL1:CLOCK,NPAS2 activates circadian gene expression snRNP Assembly PPARA activates gene expression PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Activation of gene expression by SREBF (SREBP) Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by PPARalpha Circadian Clock
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Mean platelet volume ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494 27863252) Refractive error ( 32231278)	Gut microbiota (bacterial taxa) ( 27723756) Height ( 18391951) Serum thyroid-stimulating hormone levels ( 24852370)
Interacting Genes		35 interacting genes: ABCF2 AGPAT2 ANK2 ANKFY1 ANKRD26 ANKRD50 BCL3 BRCA1 CCDC187 CD164 CSNK2B EEF1G EHMT2 EIF3D GADD45GIP1 HNRNPK HNRNPR INCA1 KCNV2 MYOM1 NOTCH2 NOTCH3 PIBF1 PTRH1 RNF11 TGM2 TGS1 THAP7 TMIE TNKS TNKS2 TTN UACA YTHDC1 ZNF512B	9 interacting genes: ANKRD28 COIL CREBBP EED EP300 HNF4A NCOA6 NOXA1 ZNF76
Entrez ID		23243	96764
HPRD ID		10651	07567
Ensembl ID		ENSG00000206560	ENSG00000137574
Uniprot IDs		A0A024R2I9 O15084	Q96RS0
PDB IDs			3EGI 3GDH
Enriched GO Terms of Interacting Partners?
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