ATG4B and GABARAPL2

Data Source:
BioGRID (enzymatic study, pull down, two hybrid)
HPRD (two hybrid)

		ATG4B	GABARAPL2
Description		autophagy related 4B cysteine peptidase	GABA type A receptor associated protein like 2
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GO Annotations	Cellular Component	Cytosol	Golgi Membrane Autophagosome Membrane Cytoplasm Autophagosome Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Cytoplasmic Vesicle
	Molecular Function	Endopeptidase Activity Cysteine-type Endopeptidase Activity Protein Binding Cysteine-type Peptidase Activity	SNARE Binding Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding ATPase Binding
	Biological Process	Proteolysis Autophagy Protein Transport Macroautophagy Positive Regulation Of Protein Catabolic Process Protein Delipidation	Autophagosome Assembly Autophagy Of Mitochondrion Intra-Golgi Vesicle-mediated Transport Autophagy Cellular Response To Nitrogen Starvation Protein Transport Macroautophagy Positive Regulation Of ATPase Activity Protein Localization To Endoplasmic Reticulum Autophagosome Maturation Negative Regulation Of Proteasomal Protein Catabolic Process
Pathways		Macroautophagy	Macroautophagy TBC/RABGAPs
Drugs
Diseases
GWAS		Asthma ( 31959851) Body mass index ( 29273807) Carotid intima media thickness ( 30510157) Crohn's disease ( 26192919) Prostate cancer ( 23535732)	Blood protein levels ( 30072576) Pancreatic cancer ( 25086665)
Interacting Genes		6 interacting genes: GABARAP GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B MAP1LC3C	89 interacting genes: AAMP AGTRAP AHNAK2 AMBRA1 ANK2 APP ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4D ATG7 BCL2L13 BNIP3L BSDC1 CALCOCO1 CALCOCO2 CLN8 CUL3 DYNLL1 DYNLL2 EGFR ERBB2 ERBB3 ERBB4 FUNDC1 GIMAP6 GOSR1 GPR37 HAP1 HSP90AB1 INSYN1 KASH5 KBTBD6 KBTBD7 KIAA1958 KIF16B KLHL5 KRTAP10-7 KRTAP10-9 LRSAM1 LZTR1 MAP1LC3B MCPH1 MEFV MLX NBR1 NEDD4 NPSR1 NSF NUDT15 OPTN OSBPL3 OSBPL7 PTPRA RAP1A RAP2A RB1CC1 RCN2 RETREG1 RETREG3 RPS2 SCYL3 SGTA SIK2 SMO SQSTM1 TAX1BP1 TBC1D25 TBC1D5 TBC1D9 TBC1D9B TEX264 TNIP1 TP53INP1 TP53INP2 TRIM21 TRIM32 TRIM45 TSR2 UBA5 ULK1 ULK2 VDR WDFY3 YWHAZ ZBTB2 ZNF774
Entrez ID		23192	11345
HPRD ID		16499	16246
Ensembl ID		ENSG00000168397	ENSG00000034713
Uniprot IDs		B3KVU2 Q9Y4P1	P60520
PDB IDs		2CY7 2D1I 2Z0D 2Z0E 2ZZP 5LXH 5LXI	4CO7 6H8C
Enriched GO Terms of Interacting Partners?
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