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FLOT2 and DXO
Data Source:
HPRD
(two hybrid)
FLOT2
DXO
Description
flotillin 2
decapping exoribonuclease
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Uropod
Endosome
Plasma Membrane
Caveola
Adherens Junction
Focal Adhesion
Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Flotillin Complex
Lamellipodium
Endocytic Vesicle
Cortical Actin Cytoskeleton
Cytoplasmic Vesicle
Vesicle
Intracellular Membrane-bounded Organelle
Cell-cell Contact Zone
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Nucleus
Nucleoplasm
Cytosol
Plasma Membrane
Molecular Function
Protein Binding
Nucleotide Binding
Magnesium Ion Binding
MRNA Binding
5'-3' Exonuclease Activity
RNA Pyrophosphohydrolase Activity
RNA NAD-cap (NAD-forming) Hydrolase Activity
Biological Process
Membrane Raft Assembly
Cell Adhesion
Epidermis Development
Negative Regulation Of Gene Expression
Regulation Of Heterotypic Cell-cell Adhesion
Regulation Of Toll-like Receptor 3 Signaling Pathway
Protein Localization To Plasma Membrane Raft
Regulation Of Myoblast Differentiation
Protein Stabilization
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Localization To Plasma Membrane
Negative Regulation Of Amyloid Precursor Protein Catabolic Process
Positive Regulation Of Establishment Of T Cell Polarity
Nuclear-transcribed MRNA Catabolic Process
MRNA Catabolic Process
RNA Destabilization
Nuclear MRNA Surveillance
Nucleic Acid Phosphodiester Bond Hydrolysis
NAD-cap Decapping
Pathways
RIPK1-mediated regulated necrosis
Regulation of necroptotic cell death
Synaptic adhesion-like molecules
Drugs
Diseases
GWAS
Mean corpuscular hemoglobin (
29403010
)
Red blood cell count (
27863252
)
Asthma (
31619474
)
Autism spectrum disorder or schizophrenia (
28540026
)
Blood protein levels (
28240269
)
Disease progression in age-related macular degeneration (
29346644
)
Inflammatory bowel disease (
28067908
)
Ulcerative colitis (
28067908
)
Interacting Genes
11 interacting genes:
APP
CAV1
CAV2
DXO
FLOT1
FYN
HGS
MAGEB4
NMNAT1
SPATA24
UBC
8 interacting genes:
EXOSC10
EXOSC4
EXOSC7
FLOT2
PRMT6
UPF1
XRN1
XRN2
Entrez ID
2319
1797
HPRD ID
00580
16186
Ensembl ID
ENSG00000132589
ENSG00000204348
Uniprot IDs
A0A024QZ62
J3QLD9
Q14254
Q6FG43
Q9BTI6
A0A024RCW8
O77932
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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