FLNC and XIRP2

Data Source:
BioGRID (pull down)

		FLNC	XIRP2
Description		filamin C	xin actin binding repeat containing 2
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GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Sarcoplasm Z Disc Sarcolemma Costamere	Stress Fiber Focal Adhesion
	Molecular Function	Actin Binding Protein Binding Cytoskeletal Protein Binding Ankyrin Binding	Actin Filament Binding
	Biological Process	Cell Junction Assembly Muscle Fiber Development	Heart Development Biological_process Actin Cytoskeleton Organization
Pathways		Cell-extracellular matrix interactions
Drugs
Diseases		Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy
GWAS		Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)	Atopic dermatitis ( 25865352) Diabetic peripheral neuropathy in type 2 diabetes ( 31127053) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Plasma renin activity levels ( 29650764)
Interacting Genes		35 interacting genes: ADRA1A ADRA1B ADRA1D CAPN3 CDC42 ENO1 FURIN HIPK3 HSPB2 INPPL1 KCND2 KY MAP2K4 MTDH MYBPC2 MYOT MYOZ1 MYOZ2 MYOZ3 NPHP1 PHLDB2 PRKAB2 PRKCA REPS1 RPS6KA2 SGCD SGCG SYNPO2 TRIM54 TRIM55 TRIM63 USP25 WNK1 XIRP1 XIRP2	5 interacting genes: DYSF FLNC LRRK2 NEB NEBL
Entrez ID		2318	129446
HPRD ID		00018	10267
Ensembl ID		ENSG00000128591	ENSG00000163092
Uniprot IDs		Q14315 Q59H94	A4UGR9
PDB IDs		1V05 2D7M 2D7N 2D7O 2D7P 2D7Q 2K9U 2NQC 3V8O 4MGX	4F14
Enriched GO Terms of Interacting Partners?
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