TTLL12 and PRR35

Data Source:
BioGRID (two hybrid)

		TTLL12	PRR35
Description		tubulin tyrosine ligase like 12	proline rich 35
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Organizing Center Spindle Midbody
	Molecular Function	Tubulin-tyrosine Ligase Activity Protein Binding ATP Binding Tubulin Binding Histone-lysine N-methyltransferase Activity H4K20me3 Modified Histone Binding	Protein Binding
	Biological Process	Regulation Of Mitotic Cell Cycle Protein Phosphopantetheinylation Histone Lysine Methylation Innate Immune Response Negative Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Histone H4-K20 Methylation
Pathways		Carboxyterminal post-translational modifications of tubulin
Drugs
Diseases
GWAS		Molar-incisor hypomineralization ( 23918034) Monocyte count ( 27863252) Platelet count ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		7 interacting genes: CSNK2A2 DNAJB1 EEF1A1 EEF1A2 FAM222B PRR35 SUMO2	80 interacting genes: ABHD11 ACY1 APPL2 ARMC5 ASB15 BEGAIN BIRC7 BPIFA1 C11orf1 C19orf54 CARD10 CCDC136 CNOT2 CRX CYSRT1 EXOC8 FAM168B FHL3 FRYL GIGYF1 GRAP2 HOMER3 HOOK2 HPCA HSPB2 HSPB2-C11orf52 INSC INTS11 JUP KLHL26 KRT31 KRT34 KRT35 KRTAP10-7 KRTAP12-1 KRTAP26-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 LASP1 LONRF1 LZTS2 MAGED1 MCCD1 MKRN3 MSS51 MTUS2 N4BP3 NBPF19 NOTCH2NLA OIP5 OXER1 PFDN5 PLAGL2 PPIL1 PPP1R13B PRR20A PRR20B PRR20C PRR20D PRR20E PSTPIP1 RBPMS RNF144B RUSC1 SMUG1 SPAG8 TBX19 TLE5 TRIM27 TRIM54 TRIM73 TTC19 TTLL12 UBASH3B UBXN11 USP54 ZMYND12 ZNF655
Entrez ID		23170	146325
HPRD ID		13782	10046
Ensembl ID		ENSG00000100304	ENSG00000161992
Uniprot IDs		A0A024R4U3 Q14166	P0CG20
PDB IDs
Enriched GO Terms of Interacting Partners?
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