GPATCH8 and NUMBL

Data Source:
BioGRID (two hybrid)

		GPATCH8	NUMBL
Description		G-patch domain containing 8	NUMB like endocytic adaptor protein
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus	Cytoplasm
	Molecular Function	RNA Binding Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Biological_process	Nervous System Development Axonogenesis Cytokine-mediated Signaling Pathway Protein Metabolic Process Lateral Ventricle Development Neuroblast Division In Subventricular Zone Adherens Junction Organization Positive Regulation Of Neurogenesis
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Pulse pressure ( 30578418)	Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Caffeine metabolism (plasma 3,7-dimethylxanthine (theobromine) level) ( 27702941) Carotid intima media thickness (mean) ( 31801372) Kawasaki disease ( 22446962) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730)
Interacting Genes		6 interacting genes: APH1A ATXN1 ATXN1L NUMBL RNPS1 SUMO2	23 interacting genes: ACTN1 APP ATXN1 BHLHE40 EGFR EPS15 ESRP2 GAA GPATCH8 GRIP1 MAGED1 NOTCH1 PSMA3 RBFOX1 RIPK1 SIAH1 SPSB3 TAB2 THPO TMC5 TRAF5 TRAF6 YWHAG
Entrez ID		23131	9253
HPRD ID		11089	04931
Ensembl ID		ENSG00000186566	ENSG00000105245
Uniprot IDs		Q9UKJ3	A0A0C4DGH3 A8K033 B7Z5W0 Q9Y6R0
PDB IDs			3F0W
Enriched GO Terms of Interacting Partners?
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