EMC1 and OTUD3

		EMC1	OTUD3
Description		ER membrane protein complex subunit 1	OTU deubiquitinase 3
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GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Protein-containing Complex EMC Complex	Cytoplasm Cytosol
	Molecular Function	Membrane Insertase Activity	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity
	Biological Process	Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane	Protein Deubiquitination Protein Phosphopantetheinylation Protein K11-linked Deubiquitination Protein K6-linked Deubiquitination Protein Stabilization Negative Regulation Of Protein Kinase B Signaling Protein K48-linked Deubiquitination Protein K27-linked Deubiquitination
Pathways			Ovarian tumor domain proteases Regulation of PTEN stability and activity
Drugs
Diseases
GWAS			group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP ( 31070471) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 19915572 28067908 20228798 20228799 19122664 23511034)
Interacting Genes			4 interacting genes: HSD17B14 HSPA5 PTEN UBC
Entrez ID		23065	23252
HPRD ID		08306	19417
Ensembl ID		ENSG00000127463	ENSG00000169914
Uniprot IDs		Q8N766	Q5T2D3
PDB IDs		6WW7 6Z3W	4BOU
Enriched GO Terms of Interacting Partners?
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