EMC1 and PADI2

Data Source:
BioGRID (affinity chromatography technology)

		EMC1	PADI2
Description		ER membrane protein complex subunit 1	peptidyl arginine deiminase 2
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Protein-containing Complex EMC Complex	Extracellular Region Nucleus Cytoplasm Cytosol Transcriptionally Active Chromatin Azurophil Granule Lumen Extracellular Exosome
	Molecular Function	Membrane Insertase Activity	Protein-arginine Deiminase Activity Calcium Ion Binding Estrogen Receptor Binding Protein Homodimerization Activity
	Biological Process	Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane	Chromatin Organization Regulation Of Chromatin Disassembly Protein Citrullination Substantia Nigra Development Intracellular Estrogen Receptor Signaling Pathway Histone H3-R26 Citrullination Histone Citrullination Neutrophil Degranulation Chromatin-mediated Maintenance Of Transcription Negative Regulation Of Chemokine-mediated Signaling Pathway Negative Regulation Of Lymphocyte Chemotaxis Cellular Response To Leukemia Inhibitory Factor
Pathways			Chromatin modifying enzymes Neutrophil degranulation
Drugs			Citrulline
Diseases
GWAS			Gut microbiota relative abundance (Ruminococcus belonging to family Lachnospiraceae) ( 33208821) Hemoglobin ( 32888494) Prudent dietary pattern ( 28644415) Rheumatoid arthritis ( 30423114) Visceral fat ( 30942860)
Interacting Genes
Entrez ID		23065	11240
HPRD ID		08306	06396
Ensembl ID		ENSG00000127463	ENSG00000117115
Uniprot IDs		Q8N766	Q9Y2J8
PDB IDs		6WW7 6Z3W	4N20 4N22 4N24 4N25 4N26 4N28 4N2A 4N2B 4N2C 4N2D 4N2E 4N2F 4N2G 4N2H 4N2I 4N2K 4N2L 4N2M 4N2N
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?