WDTC1 and MED23

Data Source:
HPRD (two hybrid)

		WDTC1	MED23
Description		WD and tetratricopeptide repeats 1	mediator complex subunit 23
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Cul4-RING E3 Ubiquitin Ligase Complex	Nucleoplasm Transcription Regulator Complex Mediator Complex
	Molecular Function	Enzyme Inhibitor Activity Protein Binding Histone Binding Histone Deacetylase Binding	Transcription Coactivator Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Glucose Metabolic Process Regulation Of Cell Size Protein Ubiquitination Cellular Response To Insulin Stimulus Multicellular Organism Growth Negative Regulation Of Catalytic Activity Post-translational Protein Modification Negative Regulation Of Fatty Acid Biosynthetic Process Cellular Chemical Homeostasis	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated
Pathways		Neddylation	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS			L-arginine levels ( 25245031) Type 2 diabetes ( 30054458)
Interacting Genes		3 interacting genes: DDB1 MED23 MED4	15 interacting genes: CEBPB CTDP1 ELF3 ESR1 ESR2 ETS1 FOXJ3 MED13 MED9 NCOA6 PUM2 RELA SREBF1 VDR WDTC1
Entrez ID		23038	9439
HPRD ID		10307	05436
Ensembl ID		ENSG00000142784	ENSG00000112282
Uniprot IDs		Q8N5D0	Q05DL5 Q9ULK4
PDB IDs		3I7N	6H02
Enriched GO Terms of Interacting Partners?
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