PDZRN3 and EFNB2

Data Source:
HPRD (two hybrid)

		PDZRN3	EFNB2
Description		PDZ domain containing ring finger 3	ephrin B2
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GO Annotations	Cellular Component	Cytoplasm Neuromuscular Junction	Plasma Membrane Integral Component Of Plasma Membrane Adherens Junction Focal Adhesion Glutamatergic Synapse Integral Component Of Presynaptic Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ubiquitin Protein Ligase Activity	Virus Receptor Activity Protein Binding Ephrin Receptor Binding
	Biological Process	Neuromuscular Junction Development Protein Ubiquitination	Cell Migration Involved In Sprouting Angiogenesis Cell Adhesion Cell-cell Signaling Axon Guidance Positive Regulation Of Cell Population Proliferation Anatomical Structure Morphogenesis Negative Regulation Of Neuron Projection Development Viral Entry Into Host Cell Ephrin Receptor Signaling Pathway Blood Vessel Morphogenesis Regulation Of Chemotaxis Presynapse Assembly Positive Regulation Of Neuron Death Positive Regulation Of Cardiac Muscle Cell Differentiation
Pathways			EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells
Drugs
Diseases
GWAS		Dialysis-related mortality ( 21546767) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 32602732) Mercury levels ( 26025379) Mitochondrial DNA copy number (white blood cells) ( 30704525) PR interval ( 30679814 30046033 32439900)	Left superior temporal gyrus thickness (schizophrenia interaction) ( 26249676) Metabolite levels ( 23823483) Pediatric autoimmune diseases ( 26301688) Subcutaneous adipose tissue ( 26480920)
Interacting Genes		7 interacting genes: BMPR2 EFNB2 LNX1 LNX2 RPS6KA1 SLC5A8 UBE2D2	23 interacting genes: ANKRD46 DLG4 EPHA3 EPHA4 EPHB1 EPHB2 EPHB4 EPHB6 GRIP1 GRM1 GRM5 HOMER1 NCK2 PDZRN3 PECAM1 PICK1 PSEN1 PTPN13 RELN RGS3 RHBDL2 SDCBP SRC
Entrez ID		23024	1948
HPRD ID		15115	02754
Ensembl ID		ENSG00000121440	ENSG00000125266
Uniprot IDs		B7Z2I8 B7Z5Q3 B7Z5X9 B7ZAG0 E7ENB6 Q9UPQ7	P52799
PDB IDs		1UHP 1WH1	2HLE 2I85 2VSK 2VSM 2WO2 3GXU 4UF7 6P7Y 6PDL
Enriched GO Terms of Interacting Partners?
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