RUFY3 and ABI3

Data Source:
BioGRID (two hybrid)

		RUFY3	ABI3
Description		RUN and FYVE domain containing 3	ABI family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Endomembrane System Membrane Lamellipodium Cell Junction Filopodium Axon Dendrite Growth Cone Neuronal Cell Body Perikaryon	Intracellular Anatomical Structure Cytoplasm Membrane Lamellipodium
	Molecular Function	Protein Binding	Protein Binding SH3 Domain Binding Identical Protein Binding
	Biological Process	Actin Filament Organization Positive Regulation Of Cell Migration Positive Regulation Of Axon Extension Regulation Of Axonogenesis Negative Regulation Of Axonogenesis Positive Regulation Of Intracellular Protein Transport Regulation Of Establishment Of Cell Polarity	Peptidyl-tyrosine Phosphorylation Regulation Of Cell Migration
Pathways
Drugs
Diseases
GWAS			Alzheimer's disease (late onset) ( 28714976) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Asthma ( 31619474) Family history of Alzheimer's disease ( 30617256) Prostate cancer ( 23535732) Refractive error ( 32231278)
Interacting Genes		5 interacting genes: ABI3 APP CAPN3 RAB33A UNC119	77 interacting genes: ABI2 ABI3BP ACTN3 AGTR1 ARHGAP9 ARMC7 BAIAP2L2 BFSP2 BLOC1S5 CENPQ CEP170P1 CEP44 CYFIP2 DESI1 DTNB DTNBP1 EIF3H EIF3M EMILIN1 ENAH EVL FAM124B FARSA FBF1 GNG13 GOLM1 GRB2 HOMER1 HOMER2 HOMER3 IFT20 IHO1 KANK2 KIAA0408 KIFC3 KLC3 KLC4 KRT13 KRT14 KRT15 KRT24 KRT28 KRT31 KRT35 KRT36 KRT38 MAGEA12 MED29 MIS18A MRFAP1 MRFAP1L1 NCK2 NDEL1 NHSL2 NUP58 OIP5 PAK1 PAK2 PSMA1 RUFY3 RUNX1T1 SH3BP1 SMARCD1 SNAP23 SOS1 STX1A STX2 SUFU TMEM147 TRAF4 TXN2 VARS2 VASP WAS WASF1 WASF2 WASHC1
Entrez ID		22902	51225
HPRD ID		15251	05900
Ensembl ID		ENSG00000018189	ENSG00000108798
Uniprot IDs		B4DG59 B4DKC2 Q7L099	Q9P2A4
PDB IDs
Enriched GO Terms of Interacting Partners?
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