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IKZF3 and MYO15B
Data Source:
BioGRID
(two hybrid)
IKZF3
MYO15B
Description
IKAROS family zinc finger 3
myosin XVB
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
Histone Deacetylase Binding
Sequence-specific DNA Binding
Metal Ion Binding
Promoter-specific Chromatin Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Mesoderm Development
Response To Bacterium
Regulation Of B Cell Proliferation
B Cell Activation
Regulation Of Apoptotic Process
Regulation Of B Cell Differentiation
Regulation Of Lymphocyte Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS
Acute lymphoblastic leukemia (childhood) (
29348612
)
Asthma (
31959851
31619474
28461288
)
Asthma (moderate or severe) (
30552067
)
Asthma and hay fever (
24388013
)
Asthma or allergic disease (pleiotropy) (
29785011
)
Atopic march (
26542096
)
Bronchial hyperresponsiveness in asthma (
27439200
)
Crohn's disease (
28067908
21102463
)
Eosinophil counts (
32888494
27863252
)
Eosinophil percentage of granulocytes (
27863252
)
Eosinophil percentage of white cells (
32888494
27863252
)
Inflammatory bowel disease (
28067908
23128233
)
Lymphocyte counts (
29403010
32888494
27863252
)
Lymphocyte percentage of white cells (
32888494
)
Marginal zone lymphoma or systemic lupus erythematosus (
31407831
)
Monocyte count (
32888494
)
Multiple sclerosis (
31604244
24076602
)
Neutrophil percentage of granulocytes (
27863252
)
Pediatric autoimmune diseases (
26301688
)
Polycystic ovary syndrome (
30343302
)
Primary biliary cholangitis (
19458352
23000144
20639880
26394269
28062665
30643196
)
Primary biliary cirrhosis (
22961000
)
Refractive error (
32231278
)
Rheumatoid arthritis (
30423114
23143596
24390342
20453842
)
Rheumatoid arthritis (ACPA-positive) (
23143596
24532676
)
Selective IgA deficiency (
27723758
)
Self-reported allergy (
23817569
)
Systemic lupus erythematosus (
27399966
26502338
)
Systemic lupus erythematosus and Systemic sclerosis (
23740937
)
Systemic sclerosis (
31672989
)
Type 1 diabetes (
30659077
25751624
)
Ulcerative colitis (
28067908
20228799
21297633
)
Interacting Genes
157 interacting genes:
ABLIM3
AKAP10
AKAP9
ANKS1A
AQP1
ARMC7
ARNT2
ATP6V0D1
ATP6V0D2
ATPAF2
ATXN7L2
BCAS2
BCL2L1
BLK
BLZF1
BYSL
C1orf109
C2CD6
CABP4
CABP5
CARD9
CATSPER1
CCDC102B
CCDC187
CCDC24
CCDC57
CCHCR1
CDC37
CDC7
CDK4
CDKN1A
CDKN2D
CFAP206
CHCHD2
CHD3
CKS1B
CLCNKA
CRBN
CRK
CRYBA4
DGCR6
DTX2
EFHC1
EGLN3
EMC2
ENKD1
EXOC8
EXOSC5
FAM124B
FANCG
FANCL
FARS2
FBF1
FHL3
FRS3
GEM
GOLGA2
GOLGA6A
GRAP2
GRB2
HNRNPF
HNRNPLL
HOXC8
HRAS
IKZF1
IKZF4
IKZF5
ING5
KANK2
KAT5
KIF9
KIFC3
KLHL38
KRT19
LDOC1
LENG1
LGALS14
LMO1
LMO2
LMO4
LNX1
LONRF1
MAD2L2
MAGOHB
MCM7
MCRS1
MID2
MISP
MKRN3
MORN3
MRPL28
MRPL53
MYO15B
NATD1
NEK6
NFKBID
NME7
NOS3
NTAQ1
NUDT16L1
NXT2
OAZ3
OSGIN1
PCID2
PDZD4
PFDN5
PIK3R1
PIK3R2
PIN1
POLM
POLR1C
PPP1R16B
PPP1R18
PRDM1
PRKAA1
PRKAA2
PRKAB2
PSMA1
PSMF1
RAD51D
RBBP8
RCOR3
RHOA
RNF6
RUNX1
SCNM1
SMARCB1
SMARCD1
SPG21
STAMBPL1
STK16
STK26
STX11
SUMO1
TBC1D22B
TCAF1
TCAP
TCEANC
TCHP
TEKT3
TEKT4
TFAP2D
TLE5
TRAPPC6A
TRIM42
TSEN15
TSGA10IP
TSSK3
TSTD2
UBE2I
USP2
VBP1
YES1
ZGPAT
ZMYM2
ZNF587
ZNF76
95 interacting genes:
ABI2
ADAMTSL4
BEND7
BHLHB9
C11orf1
C7orf57
CARD9
CCNC
CEP57L1
COIL
CRX
DNAJA3
DUSP21
ERAS
FAM9B
FHL2
GAB2
GADD45GIP1
GFAP
GINS3
HOXA1
IHO1
IKZF3
KATNBL1
KCNJ6
KIAA0408
KIF24
KIFC3
KLF4
KLHL12
KRT13
KRT34
KRT35
KRT75
LIMS1
MTUS2
MYOZ3
NADSYN1
NBPF19
NDUFA12
NECAB2
NEDD4
NEFL
NHSL2
NKAPD1
NOTCH2NLA
NR1D2
NUP62
PAK5
PKNOX2
PLEKHA3
PNMA1
PNMA5
POU6F2
PPM1K
PPP1R32
PRKAR1B
RAD54B
RBM11
RCN1
RCN3
REL
RPH3AL
RUNDC3A
SLA
SORBS3
SPATC1L
SPRED2
SSBP4
TCF12
TCF4
TEX13A
TFIP11
TLE5
TPRN
TRAF2
TRIM14
TRIM27
TRIM29
TRIM54
TSC22D4
UBQLN2
VGLL3
ZBED1
ZBTB10
ZBTB3
ZBTB32
ZBTB8A
ZCCHC14
ZMAT1
ZNF114
ZNF438
ZNF774
ZNF837
ZNRD2
Entrez ID
22806
80022
HPRD ID
05869
Ensembl ID
ENSG00000161405
ENSG00000266714
Uniprot IDs
Q9UKT9
Q96JP2
Q9H614
PDB IDs
2DLP
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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