FHL1 and MYBPC1

Data Source:
BioGRID (pull down, two hybrid)
HPRD (in vitro, two hybrid, in vivo)

		FHL1	MYBPC1
Description		four and a half LIM domains 1	myosin binding protein C1
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion	Cytosol Myofibril Myosin Filament
	Molecular Function	Molecular_function Protein Binding Ion Channel Binding Metal Ion Binding	Actin Binding Protein Binding Structural Constituent Of Muscle Myosin Binding Titin Binding
	Biological Process	Regulation Of Membrane Depolarization Muscle Organ Development Animal Organ Morphogenesis Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Differentiation Negative Regulation Of Cell Growth Positive Regulation Of Potassium Ion Transport Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Cell Adhesion Muscle Filament Sliding
Pathways			Striated Muscle Contraction
Drugs
Diseases		X-linked myopathy with postural muscle atrophy (XMPMA) Reducing body myopathy (RBM) Scapuloperoneal myopathy (SPM) Emery-Dreifuss muscular dystrophy
GWAS			Blood protein levels ( 28240269) Lung function (FEV1) ( 24023788) Memory decline ( 31985465)
Interacting Genes		32 interacting genes: AKAP12 CBX4 CDC25C CHEK2 CLMN CSRP3 DBN1 DEAF1 DOCK9 EED ENO1 FHL2 HES1 HIVEP3 IGFBP5 LAMA4 MACF1 MYBPC1 NFIL3 PAX7 PDE4DIP PDLIM3 PRNP RBPJ RING1 SRF SRPK1 TTN TXNIP USP15 YWHAE ZBTB40	23 interacting genes: ACO1 AMOT ANKRD1 ASH2L C1QTNF9 CALM1 CAPN3 CLIP4 DNAJB5 DNAJB6 DYSF FHL1 FHL2 FHL3 KLHL41 MEOX2 MYBPC2 NCF1 RAF1 SGCG TRIM55 TRIM63 TTN
Entrez ID		2273	4604
HPRD ID		02157	01185
Ensembl ID		ENSG00000022267	ENSG00000196091
Uniprot IDs		B7Z9A1 Q13642 Q5JXI2	A8KAB1 B3KPP3 Q00872 Q86TA8
PDB IDs		1X63 2CUP 2CUR 2EGQ	1X44 2DAV 2YUV 2YUW 2YUX 2YUZ 2YXM
Enriched GO Terms of Interacting Partners?
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