ADGRF5 and FNDC3B

Data Source:
BioGRID (two hybrid)

		ADGRF5	FNDC3B
Description		adhesion G protein-coupled receptor F5	fibronectin type III domain containing 3B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane Cytoplasmic Vesicle Apical Part Of Cell	Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding	RNA Binding
	Biological Process	Glomerular Filtration Energy Reserve Metabolic Process Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Glucose Homeostasis Negative Regulation Of Macrophage Activation Surfactant Homeostasis Fat Cell Differentiation Erythrocyte Development Pharyngeal Arch Artery Morphogenesis Positive Regulation Of Phospholipid Biosynthetic Process
Pathways		Surfactant metabolism
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Waist-hip ratio ( 28552196)	Central corneal thickness ( 32528159 31798171 29760442 30894546) Corneal hysteresis ( 30894546) Corneal resistance factor ( 31246245 30894546) Corneal structure ( 23291589) Coronary artery disease ( 29212778 33020668) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Glycated hemoglobin levels ( 28898252) Heart rate ( 23583979) Height ( 28552196 25282103 25429064 23563607 31562340) Hip circumference adjusted for BMI ( 28552196 25673412) Immature fraction of reticulocytes ( 32888494 27863252) Intraocular pressure ( 29617998 25173106 31798171 29785010 30054594 28073927 29235454) Intraocular pressure (Goldman correlated) ( 30894546) Mean corpuscular hemoglobin ( 32888494) Parkinson's disease ( 26227905) PR interval ( 32439900) Pulse pressure ( 30224653) Red cell distribution width ( 32888494 27863252 28957414) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Triptolide cytotoxicity ( 26121980) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for BMI in smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412 28448500)
Interacting Genes		4 interacting genes: CABP2 FNDC3B NFYC SEC13	52 interacting genes: ABHD11 ABHD8 ADGRF5 BBS2 BICRAL BRWD1 C10orf55 C10orf82 C19orf54 C22orf15 CAMK2D CAPN3 CEMP1 DAPL1 DUSP10 ERCC6 GAS2L3 HAPLN2 KLHDC7B KRTAP11-1 L3MBTL3 MBD3L1 MCCD1 MVP NDUFAB1 PIK3R4 POGZ POU6F2 PRKAA2 REL RUSC1 SPSB2 SRARP STPG4 SUOX TEKT5 TEPSIN TESMIN TEX43 TEX48 TIAM1 TOX4 TRAF2 TRIM35 TRIM42 TRIP13 TTN UBAP2 USP54 VAC14 YPEL3 ZMYND19
Entrez ID		221395	64778
HPRD ID		11010	10943
Ensembl ID		ENSG00000069122	ENSG00000075420
Uniprot IDs		Q8IZF2	Q53EP0
PDB IDs
Enriched GO Terms of Interacting Partners?
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