ALKBH3 and AK8

Data Source:
BioGRID (two hybrid)

		ALKBH3	AK8
Description		alkB homolog 3, alpha-ketoglutarate dependent dioxygenase	adenylate kinase 8
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Cytosol	Cytoplasm Cytosol Axoneme Sperm Flagellum
	Molecular Function	Protein Binding Ferrous Iron Binding L-ascorbic Acid Binding DNA-N1-methyladenine Dioxygenase Activity RNA N1-methyladenosine Dioxygenase Activity	Adenylate Kinase Activity Cytidylate Kinase Activity Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding
	Biological Process	DNA Repair DNA Dealkylation Involved In DNA Repair Cell Population Proliferation Oxidative Single-stranded DNA Demethylation Oxidative Single-stranded RNA Demethylation	Nucleoside Diphosphate Phosphorylation Nucleoside Triphosphate Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Ventricular System Development Nucleoside Monophosphate Phosphorylation
Pathways		ALKBH3 mediated reversal of alkylation damage	Interconversion of nucleotide di- and triphosphates
Drugs		Ascorbic acid	Bis(Adenosine)-5'-Pentaphosphate
Diseases
GWAS		Chronotype ( 30696823) Morning person ( 30696823)	Obesity-related traits ( 23251661)
Interacting Genes		12 interacting genes: AK8 FBXO7 GLRX3 GOLGA2 IKZF1 LNX1 OTUD4 SRPK1 SRPK2 TRIM55 TRIM63 ZDHHC17	16 interacting genes: ALKBH3 CCDC102B CDK18 CNTF DPY30 FBXO7 HAUS1 MAP3K7CL MCM7 MID1IP1 PRMT6 RBM39 SMG9 SYT17 UBE2Z ZMAT2
Entrez ID		221120	158067
HPRD ID		16793	12991
Ensembl ID		ENSG00000166199	ENSG00000165695
Uniprot IDs		Q96Q83	Q96MA6
PDB IDs		2IUW
Enriched GO Terms of Interacting Partners?
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