FANCE and FANCD2

Data Source:
HPRD (two hybrid)

		FANCE	FANCD2
Description		FA complementation group E	FA complementation group D2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Fanconi Anaemia Nuclear Complex	Condensed Chromosome Nucleus Nucleoplasm Nucleolus Cytosol Nuclear Body
	Molecular Function	Molecular_function	Protein Binding DNA Polymerase Binding
	Biological Process	Interstrand Cross-link Repair	Homologous Chromosome Pairing At Meiosis Gamete Generation Response To Gamma Radiation Intra-S DNA Damage Checkpoint Cellular Response To Oxidative Stress Interstrand Cross-link Repair Regulation Of Regulatory T Cell Differentiation Brain Morphogenesis Regulation Of Inflammatory Response Regulation Of DNA-binding Transcription Factor Activity Neuronal Stem Cell Population Maintenance Double-strand Break Repair Involved In Meiotic Recombination Regulation Of CD40 Signaling Pathway
Pathways		Fanconi Anemia Pathway	Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes
Drugs
Diseases		Fanconi anemia	Fanconi anemia
GWAS		Height ( 28552196) Ovarian cancer ( 30557369) Pulmonary function (smoking interaction) ( 23284291)	Alzheimer's disease ( 24755620) Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		8 interacting genes: BRCA2 CHEK1 FANCA FANCC FANCD2 FANCF FANCG HES1	28 interacting genes: ATM ATR BLM BRCA1 BRCA2 BRIP1 FANCC FANCE FANCI FANCL H2AC4 H2BC3 H3C1 H4C1 MEN1 MRE11 NBN PCNA RAD51 TERF1 TNFRSF1A TNFRSF1B TNKS UBB UBE2T UHRF1 UHRF2 USP1
Entrez ID		2178	2177
HPRD ID		02943	01968
Ensembl ID		ENSG00000112039	ENSG00000144554
Uniprot IDs		Q9HB96	Q9BXW9
PDB IDs		2ILR	6VAA 6VAD 6VAE 6VAF
Enriched GO Terms of Interacting Partners?
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