ALCAM and ART3

Data Source:
BioGRID (two hybrid)

		ALCAM	ART3
Description		activated leukocyte cell adhesion molecule	ADP-ribosyltransferase 3 (inactive)
Image			No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Integral Component Of Plasma Membrane Focal Adhesion External Side Of Plasma Membrane Axon Dendrite Intrinsic Component Of Plasma Membrane T Cell Receptor Complex Neuronal Cell Body Extracellular Exosome	Extracellular Region Plasma Membrane Anchored Component Of Membrane Intrinsic Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	Signaling Receptor Binding Protein Binding Identical Protein Binding	NAD+ ADP-ribosyltransferase Activity NAD+-protein-arginine ADP-ribosyltransferase Activity NADP+-protein-arginine ADP-ribosyltransferase Activity
	Biological Process	Adaptive Immune Response Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Signal Transduction Motor Neuron Axon Guidance Retinal Ganglion Cell Axon Guidance Axon Extension Involved In Axon Guidance Neuron Projection Extension	Protein ADP-ribosylation Peptidyl-arginine ADP-ribosylation
Pathways		L1CAM interactions	Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 30072576 29875488) Body mass index ( 25673413) Breast cancer ( 31757997) Chronotype ( 30696823) Cortical surface area (visual PC2) ( 32198502) Erectile dysfunction in type 1 diabetes ( 22704111) Glomerular filtration rate in chronic kidney disease ( 26420894) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Initial pursuit acceleration ( 29064472) Intraocular pressure ( 29617998) Irritable mood ( 29500382) Metabolite levels ( 23823483) Ovarian disease with few adhesions ( 28333195) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Visceral fat ( 30942860)	Blood protein levels ( 30072576 29875488 28240269) Hippocampal volume ( 29274321)
Interacting Genes		3 interacting genes: ART3 CD6 EGFR	2 interacting genes: ALCAM PRKCD
Entrez ID		214	419
HPRD ID		03389	04363
Ensembl ID		ENSG00000170017	ENSG00000156219
Uniprot IDs		B3KNN9 Q13740	Q13508
PDB IDs		1KJC 5A2F
Enriched GO Terms of Interacting Partners?
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