ETF1 and MYOZ2

Data Source:
BioGRID (biochemical)

		ETF1	MYOZ2
Description		eukaryotic translation termination factor 1	myozenin 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Translation Release Factor Complex	Actin Cytoskeleton Sarcomere Z Disc
	Molecular Function	RNA Binding Translation Release Factor Activity Protein Binding Translation Termination Factor Activity Translation Release Factor Activity, Codon Specific Ribosome Binding Sequence-specific MRNA Binding	Actin Binding Protein Binding Protein Phosphatase 2B Binding Telethonin Binding FATZ Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translational Termination Translational Termination Regulation Of Translational Termination Protein Methylation	Negative Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Tissue Development Biological_process Skeletal Muscle Fiber Adaptation Sarcomere Organization Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways		Eukaryotic Translation Termination Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 28552196) California verbal learning test score ( 31596458) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) General risk tolerance (MTAG) ( 30643258) Schizophrenia ( 28991256 25056061 29483656 30285260)	HDL cholesterol levels ( 32203549) Immature fraction of reticulocytes ( 32888494) PR interval ( 32439900) Refractive error ( 32231278)
Interacting Genes		5 interacting genes: GSPT1 GSPT2 KEAP1 LIG4 PPP2CA	18 interacting genes: ACTN1 ACTN2 ACTN4 CRK DRICH1 EWSR1 FLNC HSPB2 LDB3 MBLAC1 MKRN3 MYB PDLIM3 PPP3CA PPP3CB RBPMS WWOX ZDHHC17
Entrez ID		2107	51778
HPRD ID		02616	05724
Ensembl ID		ENSG00000120705	ENSG00000172399
Uniprot IDs		B7Z7P8 P62495	Q9NPC6
PDB IDs		1DT9 2HST 2KTU 2KTV 2LGT 2LLX 2MQ6 2MQ9 3E1Y 3J5Y 3JAG 3JAH 3JAI 4D5N 4D61 5A8L 5LZT 5LZU 5LZV 6D90 6IP8 6XA1 6ZME
Enriched GO Terms of Interacting Partners?
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