EPS8 and MRPL20

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EPS8	MRPL20
Description		epidermal growth factor receptor pathway substrate 8	mitochondrial ribosomal protein L20
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GO Annotations	Cellular Component	Plasma Membrane Cell Cortex Growth Cone Vesicle Stereocilium Ruffle Membrane Synapse Extracellular Exosome	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome Mitochondrial Large Ribosomal Subunit
	Molecular Function	Actin Binding Protein Binding Small GTPase Binding Signaling Adaptor Activity	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding
	Biological Process	Rho Protein Signal Transduction Regulation Of Cell Shape Exit From Mitosis Rac Protein Signal Transduction Regulation Of Actin Filament Length Regulation Of Rho Protein Signal Transduction Dendritic Cell Migration Regulation Of Catalytic Activity Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Actin Crosslink Formation Actin Polymerization-dependent Cell Motility Positive Regulation Of Ruffle Assembly	Ribosomal Large Subunit Assembly Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways			Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Protein quantitative trait loci ( 18464913)	Diastolic blood pressure ( 30578418) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		61 interacting genes: ABI1 ACTA1 ADAM22 AIMP2 ALDH7A1 ARMC1 BAIAP2 BCKDK BLOC1S6 BORCS6 BYSL C19orf25 C6orf141 C8orf33 CASK CBL CCDC85B CSNK2B CTNNA3 CXCL2 DNALI1 DVL1 EGFR GOLGA8EP GRB2 GULP1 HNRNPC HOOK2 INPP5J ITGB1 ITGB3 ITGB5 ITSN2 MAP1LC3B MAP3K11 MRPL20 MYO15A NACC2 NFKB2 PCM1 PROSER2 RCAN3 RFXAP RSPH14 RUNX1T1 SCRN3 SERPINA5 SF3B3 SHB SHC1 SLC27A4 SMARCE1 SOS1 SRC TDP2 TEX28 TPRN USP6NL XAGE2 XRCC6 ZZZ3	11 interacting genes: ACP1 APP CALM2 CAPZB DUSP23 EPS8 ERCC6 ITSN1 OXA1L TP53BP2 USP13
Entrez ID		2059	55052
HPRD ID		02563	14746
Ensembl ID		ENSG00000151491	ENSG00000242485
Uniprot IDs		B4E3T6 Q12929	Q9BYC9
PDB IDs		2E8M	3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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