AK2 and ABCC6

Data Source:
BioGRID (two hybrid)

		AK2	ABCC6
Description		adenylate kinase 2	ATP binding cassette subfamily C member 6
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Intermembrane Space Extracellular Exosome Sperm Mitochondrial Sheath	Nucleoplasm Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane
	Molecular Function	Adenylate Kinase Activity Protein Binding ATP Binding	Transporter Activity ATP Binding ABC-type Xenobiotic Transporter Activity ABC-type Glutathione S-conjugate Transporter Activity ATPase Activity Inorganic Diphosphate Transmembrane Transporter Activity ATPase-coupled Transmembrane Transporter Activity
	Biological Process	ADP Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Phosphorylation AMP Metabolic Process ATP Metabolic Process Nucleoside Monophosphate Phosphorylation	Drug Transmembrane Transport Visual Perception ATP Transport Inorganic Diphosphate Transport Response To Drug Xenobiotic Transport Transmembrane Transport Leukotriene Transport Anion Transmembrane Transport
Pathways		Interconversion of nucleotide di- and triphosphates	ABC-family proteins mediated transport Defective ABCC6 causes PXE
Drugs		Bis(Adenosine)-5'-Pentaphosphate Imidazole	ATP
Diseases			Pseudoxanthoma elasticum, including: Pseudoxanthoma elasticum (PXE); Pseudoxanthoma elasticum-like disorder with multiple coagulation factor deficiency
GWAS		Gut microbiota (beta diversity) ( 27723756)	Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Multiple myeloma (survival) ( 26198393) Red blood cell count ( 32888494)
Interacting Genes		4 interacting genes: ABCC5 ABCC6 SHBG TRIM54	5 interacting genes: A1BG AK2 CRYL1 FURIN NR4A1
Entrez ID		204	368
HPRD ID		00047	04453
Ensembl ID		ENSG00000004455	ENSG00000091262
Uniprot IDs		A0A140VK93 F8VY04 F8W1A4 G3V213 P54819	O95255
PDB IDs		2C9Y	6BZR 6BZS 6NLO 6P7F
Enriched GO Terms of Interacting Partners?
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