VMA21 and THSD7A

Data Source:
BioGRID (two hybrid)

		VMA21	THSD7A
Description		vacuolar ATPase assembly factor VMA21	thrombospondin type 1 domain containing 7A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Vacuole Endoplasmic Reticulum Membrane ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Extracellular Region Plasma Membrane Integral Component Of Membrane Cell Projection
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Regulation Of ATPase Activity Vacuolar Proton-transporting V-type ATPase Complex Assembly	Angiogenesis Cell Differentiation Actin Cytoskeleton Reorganization
Pathways			Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
Drugs
Diseases
GWAS			Age at voice drop ( 27182965) Alzheimer's disease (APOE e4 interaction) ( 25778476) Bipolar disorder ( 31043756) Cataracts (operation) ( 31816047) Coronary artery disease ( 29472232) Dental caries (decayed, missing and filled teeth) ( 31533690) End-stage kidney disease ( 31178898) Facial emotion recognition (angry faces) ( 28608620) Glaucoma ( 31959993 30054594) Glaucoma (primary open-angle) ( 29891935) Household income (MTAG) ( 31844048) Idiopathic dilated cardiomyopathy ( 29495422) Intraocular pressure ( 29785010 31959993) Iron status biomarkers (total iron binding capacity) ( 28334935) Lead levels in blood ( 25820613) Lung function in never smokers (low FEV1 vs high FEV1) ( 26423011) Medication use (antiglaucoma preparations and miotics) ( 31015401) Refractive error ( 32231278) Response to antiepileptic mood-stabilizing treatment in bipolar disorder ( 32627186) Resting-state electroencephalogram vigilance ( 29703947) Systolic blood pressure x educational attainment (some college) interaction (2df) ( 32372009) Tourette syndrome ( 22889924)
Interacting Genes		29 interacting genes: ABHD16A ADAM33 AQP6 ARL6IP1 ATP13A1 ATP6V0B BNIP1 CDIPT CLEC12B DAGLA HMOX2 INSIG2 LHFPL5 LYPD6B NINJ2 NIPAL3 ORMDL1 PLLP RTP2 SCD SLC25A46 SLC35E4 TECR THSD7A TMEM107 TMEM60 VAMP2 YIF1A YIPF1	14 interacting genes: AQP6 ARL13B ASAP2 CD33 COMT ELOVL5 GOLM1 HSD17B13 LHFPL1 LYVE1 SCN3B SKIL TMUB2 VMA21
Entrez ID		203547	221981
HPRD ID		18578	19401
Ensembl ID		ENSG00000160131	ENSG00000005108
Uniprot IDs		Q3ZAQ7	Q9UPZ6
PDB IDs
Enriched GO Terms of Interacting Partners?
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