MCEMP1 and ATP6V0C

Data Source:
BioGRID (two hybrid)

		MCEMP1	ATP6V0C
Description		mast cell expressed membrane protein 1	ATPase H+ transporting V0 subunit c
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Specific Granule Membrane Tertiary Granule Membrane	Lysosomal Membrane Plasma Membrane Focal Adhesion Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Azurophil Granule Membrane Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Ubiquitin Protein Ligase Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Neutrophil Degranulation	Insulin Receptor Signaling Pathway ATP Synthesis Coupled Proton Transport Viral Process Regulation Of Macroautophagy Positive Regulation Of Wnt Signaling Pathway Transferrin Transport Ion Transmembrane Transport Neutrophil Degranulation Phagosome Acidification Proton Transmembrane Transport
Pathways		Neutrophil degranulation	ROS and RNS production in phagocytes Neutrophil degranulation Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS
Interacting Genes		10 interacting genes: ARL6IP1 ASGR1 ASGR2 ATP6V0C CMTM5 CNIH1 DGAT2L6 MALL PRAF2 ZDHHC15	53 interacting genes: AQP6 ARF6 ASGR2 CD53 CD69 CD79A CERS2 CLEC14A CLEC17A CLEC2D CLIC1 CPLX4 CREB3 DNAJC1 DRD2 EDA EDA2R ERBB2 ERH EVI2A FAM210B FFAR2 GPR152 GPR25 GPR42 HSD17B13 HTR2C KLRC1 LMNA LRRC25 MARK3 MCEMP1 MDFI MSR1 NIPAL3 OPRM1 PDCD1LG2 PI16 PSMA3 RETREG3 SCN3B SLC35E3 SLC7A1 SMIM3 SPACA1 SSMEM1 STOM SUSD3 TMEM139 TMEM31 TMEM9 VSIR ZCCHC12
Entrez ID		199675	527
HPRD ID		14119	00162
Ensembl ID		ENSG00000183019	ENSG00000185883
Uniprot IDs		A0A384NYE9 Q8IX19	P27449
PDB IDs
Enriched GO Terms of Interacting Partners?
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