ZNF48 and APOBEC3C

Data Source:
BioGRID (two hybrid)

		ZNF48	APOBEC3C
Description		zinc finger protein 48	apolipoprotein B mRNA editing enzyme catalytic subunit 3C
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	P-body Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Metal Ion Binding	RNA Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Deoxycytidine Deaminase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Cytidine Deamination Negative Regulation Of Transposition Viral Process Cytidine To Uridine Editing Negative Regulation Of Viral Genome Replication Innate Immune Response Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Defense Response To Virus DNA Cytosine Deamination DNA Demethylation
Pathways			mRNA Editing: C to U Conversion Formation of the Editosome
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)	Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
Interacting Genes		18 interacting genes: APOBEC3C BYSL CEP55 EIF3E FNDC11 GOLGA2 GOLGA6L9 HOOK2 MORF4L2 MTUS2 OSBPL3 PRPF31 SF3B4 TACC1 TLE5 TRIM41 ZNF774 ZNF792	17 interacting genes: CHTOP FBXO7 HHEX HNRNPK PRR3 RBMX RBMY1A1 RBMY1F RBMY1J SHBG SRPK2 TRAF3 TRIB3 ZNF250 ZNF408 ZNF48 ZNF581
Entrez ID		197407	27350
HPRD ID		15836	09671
Ensembl ID		ENSG00000180035	ENSG00000244509
Uniprot IDs		A0A087WVT1 Q96MX3	Q9NRW3
PDB IDs			3VM8 3VOW
Enriched GO Terms of Interacting Partners?
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