EDN2 and SRP72

Data Source:
BioGRID (affinity chromatography technology)

		EDN2	SRP72
Description		endothelin 2	signal recognition particle 72
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Endoplasmic Reticulum Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Signal Recognition Particle
	Molecular Function	Hormone Activity Endothelin B Receptor Binding	RNA Binding Signal Recognition Particle Binding Protein Binding 7S RNA Binding TPR Domain Binding Ribosome Binding
	Biological Process	Prostaglandin Biosynthetic Process Temperature Homeostasis Positive Regulation Of Leukocyte Chemotaxis Hormonal Regulation Of The Force Of Heart Contraction Positive Regulation Of The Force Of Heart Contraction By Chemical Signal Regulation Of Systemic Arterial Blood Pressure By Endothelin Cellular Calcium Ion Homeostasis Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Cell Population Proliferation Positive Regulation Of Heart Rate Artery Smooth Muscle Contraction Vein Smooth Muscle Contraction Cytokine-mediated Signaling Pathway Regulation Of Vasoconstriction Calcium-mediated Signaling Neutrophil Chemotaxis Macrophage Activation Vasoconstriction Positive Regulation Of Smooth Muscle Contraction Inositol Phosphate-mediated Signaling Macrophage Chemotaxis Lung Alveolus Development Positive Regulation Of Prostaglandin-endoperoxide Synthase Activity Energy Homeostasis	SRP-dependent Cotranslational Protein Targeting To Membrane
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events	SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Phenylephrine infusion rate during anesthesia ( 31455332) PR interval ( 32439900) Squamous cell lung carcinoma ( 28604730)	Airflow obstruction ( 22837378)
Interacting Genes		3 interacting genes: CMA1 KEL MME	10 interacting genes: CASP3 CASP6 CDC42 FCHSD2 HSPB1 PYGM SKIL SRP68 SULT2B1 TULP3
Entrez ID		1907	6731
HPRD ID		07173	03671
Ensembl ID		ENSG00000127129	ENSG00000174780
Uniprot IDs		P20800	O76094 V9HWK0
PDB IDs			5M72 5M73 5WRV 5WRW
Enriched GO Terms of Interacting Partners?
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