NR0B1 and EEF2KMT

Data Source:
BioGRID (two hybrid)

		NR0B1	EEF2KMT
Description		nuclear receptor subfamily 0 group B member 1	eukaryotic elongation factor 2 lysine methyltransferase
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Membrane Nuclear Speck Centriolar Satellite Polysomal Ribosome Intracellular Membrane-bounded Organelle	Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	Transcription Corepressor Activity RNA Binding Protein Binding Transcription Factor Binding Protein Domain Specific Binding DNA Hairpin Binding Steroid Hormone Receptor Binding Protein Homodimerization Activity	Protein Binding Protein-lysine N-methyltransferase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Spermatogenesis Protein Localization Gonad Development Male Gonad Development Negative Regulation Of Steroid Biosynthetic Process Hypothalamus Development Pituitary Gland Development Male Sex Determination Adrenal Gland Development Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Leydig Cell Differentiation Response To Immobilization Stress Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Sertoli Cell Differentiation	Protein Methylation Peptidyl-lysine Trimethylation
Pathways			Protein methylation
Drugs		Dexamethasone Dexamethasone acetate
Diseases		Glycerol kinase deficiency (GKD), including: Hyperglycerolemia; Chromosome Xp21 deletion syndrome; Adrenal hypoplasia, congenital (AHC); Duchenne muscular dystrophy (DMD) 46,XY disorders of sex development (Disorders of gonadal development), including: Gonadal agenesis; Complete and partial gonadal dysgenesis; Testis regression; Ovotesticular DSD
GWAS
Interacting Genes		17 interacting genes: AR COPS2 EEF2KMT ESR1 ESR2 ESRRA ESRRG NR3C1 NR5A1 NRIP1 PGR POU5F1 PPARG RNF31 RORA SNW1 SREBF1	12 interacting genes: HPRT1 IFT88 KIAA1328 LNX1 NR0B1 PICK1 PRKAR1B PRTFDC1 TRIP13 ZNF213 ZNF35 ZNF620
Entrez ID		190	196483
HPRD ID		08362	18018
Ensembl ID		ENSG00000169297	ENSG00000118894
Uniprot IDs		F1D8P4 P51843	K7ES84 Q96G04
PDB IDs		4RWV
Enriched GO Terms of Interacting Partners?
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