DPT and LOX

Data Source:
HPRD (in vivo)

		DPT	LOX
Description		dermatopontin	lysyl oxidase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Collagen-containing Extracellular Matrix	Extracellular Region Collagen Trimer Extracellular Space Nucleus Extracellular Matrix
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding	Protein-lysine 6-oxidase Activity Copper Ion Binding Protein Binding Collagen Binding
	Biological Process	Cell Adhesion Negative Regulation Of Cell Population Proliferation Collagen Fibril Organization	Osteoblast Differentiation Regulation Of Protein Phosphorylation Cellular Protein Modification Process Heart Development Regulation Of Gene Expression Regulation Of Striated Muscle Tissue Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Peptidyl-lysine Oxidation Protein Phosphopantetheinylation Extracellular Matrix Organization Collagen Fibril Organization Bone Mineralization Lung Development Platelet-derived Growth Factor Receptor-beta Signaling Pathway Ascending Aorta Development Descending Aorta Development Wound Healing Response To Drug Regulation Of Apoptotic Process Protein Kinase B Signaling Regulation Of Megakaryocyte Differentiation Muscle Cell Cellular Homeostasis Elastic Fiber Assembly Blood Vessel Morphogenesis Response To Steroid Hormone Muscle Fiber Development Cell Chemotaxis Connective Tissue Development DNA Biosynthetic Process Regulation Of Receptor Binding Regulation Of Bone Development Cellular Response To Chemokine Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway
Pathways			Elastic fibre formation Crosslinking of collagen fibrils
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Diisocyanate-induced asthma ( 25918132) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 32602732) Morbidity-free survival ( 17903295) PR interval ( 32439900) Rosacea symptom severity ( 29771307)	Central corneal thickness ( 32528159) Coronary artery disease ( 28714974) Intraocular pressure ( 29617998) Lung function (FEV1/FVC) ( 30804560) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		4 interacting genes: BAG6 DCN LOX TGFB1	8 interacting genes: DHDDS DPT ELN H1-1 H1-5 H2BC11 H2BC21 RAF1
Entrez ID		1805	4015
HPRD ID		00510	01087
Ensembl ID		ENSG00000143196	ENSG00000113083
Uniprot IDs		Q07507	B0AZT2 B7ZAJ4 D0PNI2 P28300
PDB IDs
Enriched GO Terms of Interacting Partners?
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