DPEP1 and APPBP2

Data Source:
BioGRID (two hybrid)

		DPEP1	APPBP2
Description		dipeptidase 1	amyloid beta precursor protein binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleoplasm Plasma Membrane Apical Plasma Membrane Cell Junction Anchored Component Of Membrane Microvillus Membrane Apical Part Of Cell Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Microtubule Microtubule Associated Complex Cytoplasmic Vesicle Membrane
	Molecular Function	Protein Binding Metalloexopeptidase Activity Zinc Ion Binding Beta-lactamase Activity GPI Anchor Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Metallodipeptidase Activity Modified Amino Acid Binding	Microtubule Motor Activity Protein Binding
	Biological Process	Proteolysis Lipid Metabolic Process Leukotriene Metabolic Process Glutathione Metabolic Process Glutathione Catabolic Process Xenobiotic Metabolic Process Apoptotic Process Inflammatory Response Antibiotic Metabolic Process Negative Regulation Of Cell Migration Neutrophil Chemotaxis Cellular Response To Drug Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Homocysteine Metabolic Process Cellular Response To Calcium Ion Cellular Response To Nitric Oxide Cellular Lactam Catabolic Process	Intracellular Protein Transport Intracellular Transport
Pathways		Synthesis of Leukotrienes (LT) and Eoxins (EX) Aflatoxin activation and detoxification LTC4-CYSLTR mediated IL4 production
Drugs		Cilastatin
Diseases
GWAS		Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Chronic kidney disease ( 29124443) Creatinine levels ( 29124443) Diastolic blood pressure ( 27841878 27618447 27618448) Estimated glomerular filtration rate ( 31451708 29124443 30604766) Glomerular filtration rate ( 27588450) Glomerular filtration rate (creatinine) ( 28452372) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Height ( 31562340) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Homocysteine levels ( 23824729) Hypertension ( 27618447) Hyperuricemia ( 29124443) Mean reticulocyte volume ( 32888494) Red vs. brown/black hair color ( 30531825) Serum uric acid levels ( 29124443) Systolic blood pressure ( 27841878 27618447) Urinary albumin-to-creatinine ratio ( 31511532) Urinary metabolite levels in chronic kidney disease ( 31959995)	Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Waist-hip ratio ( 28552196)
Interacting Genes		2 interacting genes: APPBP2 KIFBP	120 interacting genes: - AADAC ACTN1 AHCY AIM2 AK3 ALDH1L1 ANKRD10 APP AR ARMCX5 ATP13A1 BCL7A BIN2 C1orf50 C6orf226 CALM3 CCDC167 CCDC85C CCNL1 CDK16 CHMP5 CIBAR1 CLCN1 CNTFR COL24A1 CORO2B CREB3 CSNK1G2 CST2 CTC1 CYBA DCD DHRS2 DHX16 DOLK DPEP1 DPYS EID3 ERO1A FAM107A FSTL1 FXYD7 GALNT3 GCSAM GP9 GPRC5C GSTP1 H2AC15 HGFAC HIPK4 HSD3B7 HSPA4 ITGB4 ITGB5 KHK KIF6 KLF11 KLHL35 LANCL2 LONRF3 LUC7L2 LUZP4 MAN2B2 MCOLN1 MFSD3 MGAT4B MLLT3 MMP28 MSH2 MSLN MUL1 MYLK NFYA NPRL3 PCSK5 PI4KAP2 PNPLA5 PPIL6 PPP1R8 PRKAA2 PRKACB PSAP PTCH1 PYROXD2 RAB7B RASSF5 RHEB RILPL1 RNF128 RNF34 RNGTT RRS1 SELENOI SELENOV SLC22A6 SLC25A23 SLC7A10 SLC9A3R1 SNX5 SPDYE2 SPDYE2B ST8SIA5 SYNRG SYT11 TAF11 TAFA4 TBL3 TCF25 TNP2 TRMT2A UBE2R2 UGGT2 WAS WDR24 WFIKKN1 WNT5B ZC3H10 ZCCHC12 ZNF747
Entrez ID		1800	10513
HPRD ID		01563	05616
Ensembl ID		ENSG00000015413	ENSG00000062725
Uniprot IDs		A0A140VJI3 P16444	A0A024QZ47 Q92624
PDB IDs		1ITQ 1ITU
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?