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DYNC1H1 and LINC01554
Data Source:
BioGRID
(unspecified method)
DYNC1H1
LINC01554
Description
dynein cytoplasmic 1 heavy chain 1
long intergenic non-protein coding RNA 1554
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Centrosome
Cytosol
Cytoplasmic Dynein Complex
Microtubule
Cytoplasmic Microtubule
Cell Cortex
Membrane
Dynein Complex
Azurophil Granule Lumen
Extracellular Exosome
Axon Cytoplasm
Molecular Function
RNA Binding
Protein Binding
ATP Binding
ATP-dependent Microtubule Motor Activity, Minus-end-directed
Dynein Intermediate Chain Binding
Dynein Light Intermediate Chain Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Microtubule-based Movement
Mitotic Spindle Organization
Nuclear Migration
Retrograde Axonal Transport
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Cytoplasmic Microtubule Organization
Positive Regulation Of Intracellular Transport
P-body Assembly
Stress Granule Assembly
Neutrophil Degranulation
Establishment Of Spindle Localization
Cell Division
Regulation Of Mitotic Spindle Organization
Minus-end-directed Vesicle Transport Along Microtubule
Regulation Of Metaphase Plate Congression
Ciliary Basal Body-plasma Membrane Docking
Positive Regulation Of Cold-induced Thermogenesis
Positive Regulation Of Spindle Assembly
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
RHO GTPases Activate Formins
Neutrophil degranulation
COPI-mediated anterograde transport
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
AURKA Activation by TPX2
HCMV Early Events
Aggrephagy
Aggrephagy
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
Distal hereditary motor neuropathies (dHMN)
GWAS
Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) (
30940143
)
Interacting Genes
19 interacting genes:
BRCA1
COX20
DISC1
DUX4
DYNLL1
EGFR
KATNA1
KATNB1
LINC01554
MTNR1B
NDEL1
PRKCD
RHBDD2
SMAD2
SUMO2
TENT5A
TNIK
YWHAG
YWHAQ
141 interacting genes:
AARS1
ACADVL
ACIN1
ACTB
ACTG1
ACTN1
ACTN3
ACTR3
ALDOA
ANXA2
ANXA5
ANXA6
APEX1
ARHGAP1
ASS1
ATAD3A
ATIC
ATP5F1A
BZW2
CANX
CCT2
CCT3
CCT4
CCT6A
CCT7
CKAP4
CS
CTPS1
DDX3X
DDX46
DHX9
DNAH2
DNAJA1
DST
DYNC1H1
EDARADD
EEF1G
EEF2
EIF3A
EIF3E
EIF4A2
EIF4B
ENO1
ENO3
EPRS1
ERO1A
G3BP1
G6PD
GANAB
GAPDH
GARS1
GDI2
GPI
GTF2I
HIVEP2
HMCN1
HNRNPF
HSP90AA1
HSP90B1
HSPA1L
HSPA5
HSPA8
HSPA9
HSPD1
HYOU1
IDH1
IPO4
IPO7
IPO9
ITPR2
KARS1
KPNA1
KPNB1
KRT18
KRT7
KRT8
KRT8P3
LRPPRC
MCM7
MSN
MYO18A
NAP1L1
NAP1L4
NCBP1
NCL
NPM1
OLA1
OXCT1
PABPC1
PCBP2
PDIA3
PDIA6
PFAS
PGD
PGK1
PGM1
PHGDH
PKM
PLOD2
PMPCA
POR
PPP2R1A
PSMC1
PSMD2
PSMD7
PTBP1
RDX
RPL6
RPSA
RTCB
RTN4
SARS1
SEPTIN7
SEPTIN9
SERPINH1
SFPQ
SQSTM1
TARS1
TGFBI
THOP1
TKT
TTF2
TUBA1A
TUBA8
TUBB
TUBB2A
TUBB3
TUBB4A
TUBB4B
TUBB6
TUFM
TXNRD1
TYMP
UBA1
VCL
VCP
VIM
VPS35
WARS1
XPO1
XRCC5
Entrez ID
1778
202299
HPRD ID
02524
16896
Ensembl ID
ENSG00000197102
ENSG00000236882
Uniprot IDs
Q14204
PDB IDs
2BOR
2BOT
5NUG
5OWO
6F1T
6F1U
6F1V
6F1Y
6F38
6F3A
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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