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DLG4 and CRIPT
Data Source:
BioGRID
(pull down)
HPRD
(two hybrid, in vitro)
DLG4
CRIPT
Description
discs large MAGUK scaffold protein 4
CXXC repeat containing interactor of PDZ3 domain
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Endoplasmic Reticulum
Cytosol
Plasma Membrane
Synaptic Vesicle
Voltage-gated Potassium Channel Complex
Ionotropic Glutamate Receptor Complex
Postsynaptic Density
Cell Junction
Endocytic Vesicle Membrane
Cortical Cytoskeleton
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Neuromuscular Junction
AMPA Glutamate Receptor Complex
Dendrite Cytoplasm
Neuron Projection
Dendritic Spine
Juxtaparanode Region Of Axon
Cerebellar Mossy Fiber
Neuron Projection Terminus
Neuron Spine
Synapse
Postsynaptic Membrane
Excitatory Synapse
Synaptic Membrane
Postsynaptic Density Membrane
Glutamatergic Synapse
Cytoplasm
Postsynaptic Density
Dendrite
Neuronal Cell Body
Dendritic Spine
Dendritic Shaft
Molecular Function
Protein Binding
Protein C-terminus Binding
Kinase Binding
Protein Phosphatase Binding
PDZ Domain Binding
Beta-1 Adrenergic Receptor Binding
D1 Dopamine Receptor Binding
P2Y1 Nucleotide Receptor Binding
Acetylcholine Receptor Binding
Ionotropic Glutamate Receptor Binding
Protein-containing Complex Binding
Neuroligin Family Protein Binding
Scaffold Protein Binding
Protein Binding
Microtubule Binding
PDZ Domain Binding
Protein-containing Complex Binding
Scaffold Protein Binding
Biological Process
MAPK Cascade
Negative Regulation Of Receptor Internalization
Signal Transduction
Positive Regulation Of Cytosolic Calcium Ion Concentration
Chemical Synaptic Transmission
Nervous System Development
Learning
Synaptic Vesicle Maturation
Social Behavior
Protein Localization To Synapse
Locomotory Exploration Behavior
Cellular Response To Potassium Ion
Receptor Clustering
Establishment Of Protein Localization
Regulation Of Long-term Neuronal Synaptic Plasticity
Positive Regulation Of Synaptic Transmission
Neuromuscular Process Controlling Balance
Dendritic Spine Morphogenesis
Positive Regulation Of Protein Tyrosine Kinase Activity
Protein-containing Complex Assembly
Vocalization Behavior
AMPA Glutamate Receptor Clustering
Receptor Localization To Synapse
Cell-cell Adhesion
Postsynaptic Neurotransmitter Receptor Diffusion Trapping
Positive Regulation Of Neuron Projection Arborization
Regulation Of NMDA Receptor Activity
Positive Regulation Of Excitatory Postsynaptic Potential
Regulation Of Grooming Behavior
Cytoplasmic Microtubule Organization
Protein Localization To Microtubule
Establishment Of Protein Localization
Regulation Of Postsynaptic Density Protein 95 Clustering
Pathways
Signaling by ERBB4
Trafficking of AMPA receptors
Unblocking of NMDA receptors, glutamate binding and activation
Unblocking of NMDA receptors, glutamate binding and activation
Ras activation upon Ca2+ influx through NMDA receptor
NrCAM interactions
Activation of Ca-permeable Kainate Receptor
RHO GTPases activate CIT
RAF/MAP kinase cascade
LGI-ADAM interactions
Neurexins and neuroligins
Neurexins and neuroligins
Synaptic adhesion-like molecules
Assembly and cell surface presentation of NMDA receptors
Negative regulation of NMDA receptor-mediated neuronal transmission
Long-term potentiation
Drugs
Guanidine
Guanosine-5'-Monophosphate
Diseases
GWAS
Cholesterol, total (
24097068
25961943
)
Hematocrit (
32888494
)
Hemoglobin (
32888494
)
LDL cholesterol (
24097068
25961943
)
LDL cholesterol levels (
28334899
)
Liver enzyme levels (alkaline phosphatase) (
22001757
)
Serum alkaline phosphatase levels (
29403010
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cerebrospinal P-tau181p levels (
28247064
)
Chronotype (
30696823
)
Cortical surface area (min-P) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Cortical thickness (MOSTest) (
32665545
)
Height (
20966902
)
Pulse pressure (alcohol consumption interaction) (
24376456
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
109 interacting genes:
ACTN2
ADGRB1
ADGRL1
ADRB1
AKAP5
ARHGAP32
ARRB2
ASIC3
ATP2B2
ATP2B4
BEGAIN
CACNG2
CASK
CD46
CIT
CNKSR2
CRHR1
CRIPT
CYLD
DLG2
DLG3
DLGAP1
DLGAP2
DLGAP3
DLGAP4
DYNLL1
EFNB2
ERBB2
ERBB4
ERBIN
EXOC4
FYN
FZD1
FZD2
FZD4
FZD7
GDA
GLS2
GNG13
GRIK1
GRIK2
GRIK5
GRIN1
GRIN2A
GRIN2B
GRIN2C
GRIN2D
GRIN3A
GRIN3B
GUCY1A2
HGS
HTR2A
HTR2C
HTT
IL13RA1
KCNA1
KCNA2
KCNA3
KCNA4
KCNA5
KCND2
KCNJ10
KCNJ12
KCNJ2
KCNJ4
KHDRBS1
KIF13B
KIF1B
LIN7A
LIN7B
LRFN1
LRP1
LRP2
LRP8
LRRC1
LYN
MAP1A
MAP3K10
MAPK12
MDM2
NCKIPSD
NDOR1
NLGN1
NLGN2
NLGN3
NLGN4X
NOS1
PCDH10
PRKCA
PTK2B
PTPRG
RPS6KA1
SCN5A
SEMA4B
SEMA4C
SEMA4F
SEMA4G
SHANK1
SHANK2
SIPA1L1
SPRR2A
SRC
SYNGAP1
TAMALIN
TANC1
TRAF6
WNT3A
YES1
ZDHHC17
7 interacting genes:
DLG1
DLG2
DLG3
DLG4
PATJ
TUBB
UBQLN4
Entrez ID
1742
9419
HPRD ID
04199
05208
Ensembl ID
ENSG00000132535
ENSG00000119878
Uniprot IDs
B7Z4H2
B7Z647
B9EGL1
P78352
Q9P021
PDB IDs
1KEF
2MES
3I4W
3K82
3ZRT
5J7J
5JXB
6QJD
6QJF
6QJG
6QJI
6QJJ
6QJK
6QJL
6QJN
6SPV
6SPZ
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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