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DHX9 and ILF3
Data Source:
HPRD
(two hybrid, in vivo, in vitro)
DHX9
ILF3
Description
DExH-box helicase 9
interleukin enhancer binding factor 3
Image
GO Annotations
Cellular Component
Intracellular Anatomical Structure
Nucleus
Nucleoplasm
Perichromatin Fibrils
Nucleolus
Cytoplasm
Centrosome
Cytosol
Polysome
Actin Cytoskeleton
Membrane
RISC Complex
Nuclear Body
Protein-containing Complex
Cytoplasmic Ribonucleoprotein Granule
Polysomal Ribosome
RISC-loading Complex
CRD-mediated MRNA Stability Complex
Nuclear Stress Granule
Ribonucleoprotein Complex
Extracellular Region
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Mitochondrion
Membrane
Ribonucleoprotein Complex
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Complex Binding
Regulatory Region RNA Binding
RNA Polymerase II Transcription Factor Binding
DNA Binding
DNA Helicase Activity
DNA Replication Origin Binding
Double-stranded DNA Binding
Single-stranded DNA Binding
Transcription Coregulator Activity
Transcription Coactivator Activity
RNA Binding
RNA Helicase Activity
Double-stranded RNA Binding
Single-stranded RNA Binding
MRNA Binding
Protein Binding
ATP Binding
ATPase Activity
Nucleoside-triphosphatase Activity
Chromatin DNA Binding
3'-5' DNA/RNA Helicase Activity
3'-5' RNA Helicase Activity
SiRNA Binding
RNA Stem-loop Binding
3'-5' DNA Helicase Activity
Triplex DNA Binding
Metal Ion Binding
Nucleoside-triphosphate Diphosphatase Activity
Importin-alpha Family Protein Binding
RNA Polymerase Binding
RISC Complex Binding
Polysome Binding
Single-stranded 3'-5' DNA Helicase Activity
Sequence-specific MRNA Binding
Promoter-specific Chromatin Binding
DNA Binding
RNA Binding
Double-stranded RNA Binding
Single-stranded RNA Binding
Protein Binding
MRNA 3'-UTR AU-rich Region Binding
Biological Process
Alternative MRNA Splicing, Via Spliceosome
MRNA Splicing, Via Spliceosome
Osteoblast Differentiation
DNA Replication
DNA-templated Transcription, Termination
Regulation Of Transcription By RNA Polymerase II
Inflammatory Response
RNA Secondary Structure Unwinding
Targeting Of MRNA For Destruction Involved In RNA Interference
Positive Regulation Of Type I Interferon Production
DNA Duplex Unwinding
Positive Regulation Of Interferon-alpha Production
Positive Regulation Of Interferon-beta Production
Positive Regulation Of Interleukin-18 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Tumor Necrosis Factor Production
Cellular Protein-containing Complex Assembly
DNA-templated Viral Transcription
G-quadruplex DNA Unwinding
Innate Immune Response
Positive Regulation Of Innate Immune Response
Positive Regulation Of DNA Repair
Positive Regulation Of DNA Replication
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of RNA Export From Nucleus
Positive Regulation Of Fibroblast Proliferation
Rhythmic Process
Positive Regulation Of Viral Transcription
Regulation Of MRNA Processing
Regulation Of Defense Response To Virus By Host
Positive Regulation Of Inflammatory Response
MRNA Transport
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Response To Cytokine Stimulus
Pyroptosis
Small RNA Loading Onto RISC
CRD-mediated MRNA Stabilization
Cellular Response To Tumor Necrosis Factor
Cellular Response To Exogenous DsRNA
Protein Localization To Cytoplasmic Stress Granule
Positive Regulation Of Viral Translation
Positive Regulation Of Polysome Binding
Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity
Positive Regulation Of Gene Silencing By MiRNA
Regulation Of Cytoplasmic Translation
Positive Regulation Of Cytoplasmic Translation
Protein Phosphorylation
Negative Regulation Of Translation
Negative Regulation Of Viral Genome Replication
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Defense Response To Virus
Pathways
RIP-mediated NFkB activation via ZBP1
DEx/H-box helicases activate type I IFN and inflammatory cytokines production
mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Bipolar disorder (
31043756
)
Chronotype (
30696823
)
Height (
25282103
25429064
)
Ischemic stroke (
29531354
)
Obesity-related traits (
23251661
)
Psoriasis (
25903422
25574825
23143594
)
Psoriasis vulgaris (
26626624
)
Rheumatoid arthritis (
30423114
)
Stroke (
29531354
)
Systemic lupus erythematosus (
28714469
)
Interacting Genes
43 interacting genes:
ACTA1
AKAP8L
APBB1
BRCA1
DDX20
DDX5
DUX4
EIF2AK2
ESR1
GEMIN2
GEMIN4
GTF2B
H2AX
HDLBP
HNRNPC
HNRNPK
IL7R
ILF3
JUN
KHDRBS1
LINC01554
MBD2
NXF1
OGA
PCNA
POLR2A
PRMT1
PRPF40A
PRPF8
PTEN
RBM4
RELA
SMN1
SMN2
SNRPB
SNRPB2
SRPK1
SSRP1
STAU1
TBP
TOP2A
UBE2I
YWHAQ
38 interacting genes:
DHX9
DUX4
EIF2AK2
EP300
ERBB2
ERG
ESR1
FUS
GDF9
HNRNPH2
IL7R
KRTAP4-12
LNX1
MAGEA11
MDFI
NDRG1
PLSCR1
PPP1R12A
PRMT1
PRMT5
PTEN
RBM5
RBPMS
RNF113A
SF1
SF3B4
SMN1
SNRPC
TRIM55
TRIM63
TRIP6
UBC
UBE2D2
VPS37C
XAB2
XPO5
ZNF346
ZNF830
Entrez ID
1660
3609
HPRD ID
04386
04420
Ensembl ID
ENSG00000135829
ENSG00000129351
Uniprot IDs
B3KU66
Q08211
A0A024R7C7
Q12906
PDB IDs
3LLM
3VYX
3VYY
2L33
3P1X
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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