DCX and PPP1R9B

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		DCX	PPP1R9B
Description		doublecortin	protein phosphatase 1 regulatory subunit 9B
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Microtubule Microtubule Associated Complex Axoneme Neuron Projection	Protein Phosphatase Type 1 Complex Nucleoplasm Cytoplasm Plasma Membrane Adherens Junction Postsynaptic Density Actin Cytoskeleton Lamellipodium Filopodium Dendrite Growth Cone Cortical Actin Cytoskeleton Ruffle Membrane Neuronal Cell Body Dendritic Spine Neck Dendritic Spine Head Cytoplasmic Side Of Dendritic Spine Plasma Membrane
	Molecular Function	Protein Binding Microtubule Binding Protein Kinase Binding	Protein Kinase Activity Protein Phosphatase Inhibitor Activity Protein Binding Protein C-terminus Binding Protein Phosphatase 1 Binding Kinase Binding D2 Dopamine Receptor Binding Ion Channel Binding Actin Filament Binding
	Biological Process	Neuron Migration Nervous System Development Central Nervous System Development Axoneme Assembly Intracellular Signal Transduction Photoreceptor Cell Development Retina Development In Camera-type Eye	Regulation Of Cell Growth By Extracellular Stimulus Regulation Of Protein Phosphorylation Response To Amphetamine Developmental Process Involved In Reproduction Protein Phosphorylation Actin Filament Organization Cell Cycle Arrest Regulation Of Exit From Mitosis Aging Learning RNA Splicing Dendrite Development Cell Migration Calcium-mediated Signaling Hippocampus Development Cerebral Cortex Development Actin Filament Depolymerization Negative Regulation Of Cell Growth Neuron Projection Development Negative Regulation Of Phosphoprotein Phosphatase Activity Response To Prostaglandin E Response To Nicotine Cellular Response To Drug Response To Immobilization Stress Regulation Of Cell Population Proliferation Filopodium Assembly Response To Steroid Hormone Modulation Of Chemical Synaptic Transmission Male Mating Behavior Reproductive System Development Cellular Response To Morphine Cellular Response To Epidermal Growth Factor Stimulus Cellular Response To Estradiol Stimulus Response To Clozapine Cellular Response To Peptide Positive Regulation Of Protein Localization To Plasma Membrane Protein Localization To Actin Cytoskeleton Positive Regulation Of Protein Localization To Actin Cortical Patch Response To Kainic Acid Response To L-phenylalanine Derivative Protein Localization To Cell Periphery Regulation Of Opioid Receptor Signaling Pathway
Pathways		Neurofascin interactions
Drugs
Diseases		Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)
GWAS			Platelet distribution width ( 32888494) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		39 interacting genes: ACD AP1M1 AP2M1 APP BICD2 CALCOCO2 CDK5 FBXO25 FSD2 GOLGA2 HOOK2 IKZF1 KIFC3 KRT40 KRTAP10-8 MAPK9 MEOX1 MEOX2 MID2 MTUS2 NFASC PAFAH1B1 POT1 PPP1CA PPP1R9B RBM5 RINT1 SPAG5 SPP1 TERF1 TINF2 TRIM23 TRIM27 TRIM39 USP9X VPS52 ZBTB10 ZBTB5 ZRANB1	25 interacting genes: ACTA1 ACTN2 ADRA1A ADRA1B ADRA2A ADRA2B ADRA2C CCKAR CCKBR CDKN2A CHRM3 DCX DRD2 LRRC7 MAPK1 PPP1CA PPP1CB PPP1CC PPP1R2 PPP1R9A PRKACA RGS2 RPS6KB1 TGOLN2 TIAM1
Entrez ID		1641	84687
HPRD ID		02127	04506
Ensembl ID		ENSG00000077279	ENSG00000108819
Uniprot IDs		A8K340 O43602	Q96SB3
PDB IDs		1MJD 2BQQ 2XRP 4ATU 5IKC 5IN7 5IO9 5IOI 5IP4 6FNZ 6REV 6RF2 6RF8 6RFD
Enriched GO Terms of Interacting Partners?
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