TOR1AIP2 and TOR1A

Data Source:
HPRD (in vivo)

		TOR1AIP2	TOR1A
Description		torsin 1A interacting protein 2	torsin family 1 member A
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Nuclear Membrane	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Lumen Cytosol Cytoskeleton Synaptic Vesicle Membrane Secretory Granule Growth Cone Cytoplasmic Vesicle Membrane Nuclear Membrane Extrinsic Component Of Endoplasmic Reticulum Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	ATPase Activator Activity Protein Binding ATPase Binding	Protein Binding ATP Binding Cytoskeletal Protein Binding ATPase Activity Kinesin Binding Identical Protein Binding Unfolded Protein Binding Misfolded Protein Binding
	Biological Process	Endoplasmic Reticulum Organization Positive Regulation Of ATPase Activity Membrane Organization Protein Localization To Nuclear Envelope	Protein Deneddylation Response To Oxidative Stress Organelle Organization Nuclear Envelope Organization Cell Adhesion Neuron Projection Development Protein Localization To Nucleus Wound Healing, Spreading Of Cells Intermediate Filament Cytoskeleton Organization Synaptic Vesicle Transport Chaperone Cofactor-dependent Protein Refolding Regulation Of Dopamine Uptake Involved In Synaptic Transmission Chaperone-mediated Protein Folding ER-associated Misfolded Protein Catabolic Process Nuclear Membrane Organization Chaperone-mediated Protein Transport Positive Regulation Of Synaptic Vesicle Endocytosis Regulation Of Protein Localization To Cell Surface
Pathways			Cargo recognition for clathrin-mediated endocytosis
Drugs
Diseases			Primary torsion dystonia (PTD)
GWAS		Refractive error ( 32231278)	Prostate cancer ( 29892016) Prostate cancer (advanced) ( 29892016) Prostate cancer (early onset) ( 29892016)
Interacting Genes		5 interacting genes: RBPMS TOR1A TRIM55 TRIM63 UBC	7 interacting genes: KRTAP10-7 LMNA LRRC7 MDFI SNCA TOR1AIP2 TOR1B
Entrez ID		163590	1861
HPRD ID		10048	06897
Ensembl ID		ENSG00000169905	ENSG00000136827
Uniprot IDs		A0A6B9D1Q5 Q8NFQ8 Q9H496	B3KPA1 O14656
PDB IDs		5J1S 5J1T	5J1S 5J1T 6OIF
Enriched GO Terms of Interacting Partners?
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