ZNF497 and VWC2

Data Source:
BioGRID (two hybrid)

		ZNF497	VWC2
Description		zinc finger protein 497	von Willebrand factor C domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Basement Membrane Interstitial Matrix Extracellular Space AMPA Glutamate Receptor Complex Synapse
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding	Molecular_function Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Positive Regulation Of Cell-substrate Adhesion Negative Regulation Of BMP Signaling Pathway Positive Regulation Of Neuron Differentiation
Pathways
Drugs
Diseases
GWAS			Blood protein levels ( 30072576 29875488) Body mass index ( 28892062 25673413) Lung cancer in never smokers ( 28604730) Neurological blood protein biomarker levels ( 31320639) Post bronchodilator FEV1/FVC ratio ( 26634245) Pursuit maintenance gain ( 29064472) Serum thyroid-stimulating hormone levels ( 25436638)
Interacting Genes		39 interacting genes: CCDC136 CYSRT1 DVL3 GGA3 GOLGA6L9 HOOK2 KHDRBS2 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP4-12 KRTAP4-4 KRTAP6-3 KRTAP9-3 MCC MDFI MID2 MTUS2 NBPF19 NOTCH2NLA OSBPL3 PICK1 PTPN21 PURB SULT2B1 TNS2 TRIM41 VWC2 ZBTB8A ZNF473 ZNF526 ZNF71 ZNF792 ZNF835 ZNF837 ZRANB1	57 interacting genes: ABHD15 ADAMTSL4 ATPAF2 CAMLG CATSPER1 CNNM3 CRY2 CYSRT1 ENKD1 FAM90A1 FBXW5 FUCA2 GET3 GNE HAPLN2 HOXA1 HPCA HPCAL1 KANK2 KPRP KRTAP10-8 KRTAP13-2 KRTAP13-3 KRTAP2-3 KRTAP2-4 KRTAP5-9 LCE1A LCE1C LCE1F LCE2C LCE2D LCE3A LCE3D LCE3E LCE4A NTM OTX1 PFKFB1 POU4F2 PRPF31 SCNM1 SGTB SHFL SPRY1 TRAPPC14 UBQLN1 UBQLN2 VASN YY1 ZNF319 ZNF417 ZNF490 ZNF497 ZNF587 ZNF696 ZNF774 ZNF837
Entrez ID		162968	375567
HPRD ID		15806	18271
Ensembl ID		ENSG00000174586	ENSG00000188730
Uniprot IDs		Q6ZNH5	Q2TAL6
PDB IDs
Enriched GO Terms of Interacting Partners?
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